anti-Human C-MYC antibody for Enzyme Immunoassay

Recommended C-MYC Antibody (supplied by: Log in to see )

Antigen
V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibodies
  • MRTL
  • MYCC
  • bHLHe39
  • c-Myc
  • CMYC
  • c-myc
  • C-MYC
  • LOC100136746
  • RNCMYC
  • mMyc
  • AU016757
  • Myc2
  • Niard
  • Nird
  • MYC
  • cmyc
  • zc-myc
  • c-myc II
  • myc-B
  • myc2
  • CMyc
  • CG10798
  • D-Myc
  • DM
  • DMYc
  • Dm
  • Dmel\CG10798
  • Dmyc
  • EG:BACN5I9.1
  • anon-WO03040301.171
  • bHLHe57
  • c-MYC
  • d-myc
  • dMYC
  • dMyc
  • dMyc1
  • da
  • dm
  • dm/dMyc
  • dm/myc
  • dmyc
  • dmyc1
  • l(1)G0139
  • l(1)G0354
  • l(1)G0359
  • myc
  • MYC proto-oncogene, bHLH transcription factor
  • v-myc myelocytomatosis viral oncogene homolog
  • myelocytomatosis oncogene
  • MYC proto-oncogene, bHLH transcription factor a
  • MYC proto-oncogene, bHLH transcription factor L homeolog
  • v-myc myelocytomatosis viral oncogene homolog (avian)
  • CG10798 gene product from transcript CG10798-RB
  • MYC
  • LOC100136746
  • Myc
  • myca
  • myc.L
Epitope
pThr58
167
121
77
45
43
29
26
18
18
16
15
15
14
10
5
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
706
215
125
50
42
36
20
20
14
14
13
12
12
9
9
7
6
6
4
4
4
3
3
3
2
2
1
1
1
1
1
Host
Rabbit
378
342
29
16
8
1
Clonality
Polyclonal
Conjugate
This C-MYC antibody is un-conjugated
47
41
40
21
18
17
17
14
13
13
13
13
13
13
12
12
12
10
5
5
5
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
483
245
229
228
228
161
150
124
92
52
18
14
14
11
9
8
6
6
4
2
2
1
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Catalog No. ABIN358293
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN119683 EIA IHC (fro) IHC (p) WB HRP Mouse IgG1 C-Term Log in to see 9-00E-010 2
1 ABIN119684 EIA FACS IHC (fro) IHC (p) IP WB Mouse IgG1 C-Term Log in to see 9-00E-010 2
1 ABIN320079 EIA FACS IHC (fro) IHC (p) WB Mouse IgG1 C-Term Log in to see 9-00E-010 2
1 ABIN320077 EIA IHC (fro) IHC (p) WB Alkaline Phosphatase (AP) Mouse IgG1 C-Term Log in to see 9-00E-010 7
1 ABIN5610923 EIA WB Rabbit Ig Fraction Log in to see Polyclonal
1 ABIN5610924 EIA WB Rabbit Ig Fraction Log in to see Polyclonal
1 ABIN5610922 EIA IHC (p) WB Rabbit Ig Fraction Log in to see Polyclonal
1 ABIN950700 EIA IHC (fro) IF WB FITC Chicken Ig Fraction Log in to see Polyclonal
1 ABIN950702 EIA IHC (fro) IF IP WB Chicken Ig Fraction Log in to see Polyclonal

General

Antigen V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibodies
Epitope pThr58
(167), (121), (77), (45), (43), (29), (26), (18), (18), (16), (15), (15), (14), (10), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(706), (215), (125), (50), (42), (36), (20), (20), (14), (14), (13), (12), (12), (9), (9), (7), (6), (6), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(378), (342), (29), (16), (8), (1)
Clonality
Polyclonal
Conjugate This C-MYC antibody is un-conjugated
(47), (41), (40), (21), (18), (17), (17), (14), (13), (13), (13), (13), (13), (13), (12), (12), (12), (10), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(483), (245), (229), (228), (228), (161), (150), (124), (92), (52), (18), (14), (14), (11), (9), (8), (6), (6), (4), (2), (2), (1)
Pubmed 5 references available
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Product Details anti-C-MYC Antibody

Target Details C-MYC Application Details Handling References for anti-C-MYC antibody (ABIN358293) Images
Specificity This antibody detects MYC pThr58. Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).
Purification Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.
Isotype Ig Fraction

Target Details C-MYC

Product Details anti-C-MYC Antibody Application Details Handling References for anti-C-MYC antibody (ABIN358293) Images back to top
Antigen
Alternative Name C-Myc (MYC Antibody Abstract)
Background MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64
Molecular Weight 50434 Da
Gene ID 4609, 9606
UniProt P01106
Research Area Transcription Factors, Cancer, Cell Cycle
Pathways p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus

Application Details

Product Details anti-C-MYC Antibody Target Details C-MYC Handling References for anti-C-MYC antibody (ABIN358293) Images back to top
Application Notes ELISA: 1/1,000. Dot Blot: 1/100-1/500. Western Blot: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-C-MYC Antibody Target Details C-MYC Application Details References for anti-C-MYC antibody (ABIN358293) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-C-MYC antibody (ABIN358293)

Product Details anti-C-MYC Antibody Target Details C-MYC Application Details Handling Images back to top
Background publications

Qi, Gregory, Li, Brousal, West, Hann: "p19ARF directly and differentially controls the functions of c-Myc independently of p53." in: Nature, Vol. 431, Issue 7009, pp. 712-7, 2004

Wilda, Busch, Klose, Keller, Woessmann, Kreuder, Harbott, Borkhardt: "Level of MYC overexpression in pediatric Burkitt's lymphoma is strongly dependent on genomic breakpoint location within the MYC locus." in: Genes, chromosomes & cancer, Vol. 41, Issue 2, pp. 178-82, 2004

Domínguez-Cáceres, García-Martínez, Calcabrini, González, Porque, León, Martín-Pérez: "Prolactin induces c-Myc expression and cell survival through activation of Src/Akt pathway in lymphoid cells." in: Oncogene, Vol. 23, Issue 44, pp. 7378-90, 2004

Pap, Nawrath, Heinrich, Bosse, Baier, Hummel, Petrow, Kuchen, Michel, Gay, Müller-Ladner, Moelling, Gay: "Cooperation of Ras- and c-Myc-dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis." in: Arthritis and rheumatism, Vol. 50, Issue 9, pp. 2794-802, 2004

Ozawa, Shichiri, Fukai, Yoshimoto, Hirata: "Regulation of adrenomedullin gene transcription and degradation by the c-myc gene." in: Endocrinology, Vol. 145, Issue 9, pp. 4244-50, 2004

Images

Product Details anti-C-MYC Antibody Target Details C-MYC Application Details Handling References for anti-C-MYC antibody (ABIN358293) back to top
Supplier Images
 image for anti-V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) (pThr58) antibody (ABIN358293) anti-V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) (pThr58) antibody