anti-Human TNFRSF10B antibody for Western Blotting

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor superfamily member 10b S homeolog
  • tumor necrosis factor receptor superfamily member 10b L homeolog
  • tumor necrosis factor receptor superfamily member 10b
  • TNF receptor superfamily member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b.S
  • tnfrsf10b.L
  • tnfrsf10b
Epitope
AA 233-440
42
14
13
10
10
9
8
8
8
8
7
5
5
5
5
4
4
4
4
3
3
3
3
3
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
315
68
28
1
1
1
1
1
Host
Rabbit
186
158
8
6
2
Clonality
Polyclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
19
18
16
6
5
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
201
133
76
61
40
35
30
27
16
13
13
8
3
3
3
2
1
1
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Catalog No. ABIN5518794
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
17.056355 ABIN2855397 WB Rabbit IgG Center Log in to see Polyclonal 0
17.056355 ABIN3021808 IHC WB Rabbit IgG Log in to see Polyclonal 0
17.056355 ABIN926857 WB Rabbit N-Term Log in to see Polyclonal 0
17.056355 ABIN6135928 ICC WB Mouse Log in to see 0
16.783474 ABIN4361766 FACS ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal 37
13.803753 ABIN1980532 ICC IHC WB Rabbit IgG AA 234-435 Log in to see Polyclonal 0
13.803753 ABIN2904402 IF/ICC IHC IP WB Rabbit AA 234-435 Log in to see Polyclonal 0
13.252602 ABIN4901399 ELISA WB Mouse IgG2b Log in to see 6F6-F5-D11 0
13.252602 ABIN4901397 ELISA WB Mouse IgG1 Log in to see 7F4-F8-G11 0
13.252602 ABIN4901398 ELISA WB Mouse IgG2b Log in to see 4G12-F5-E9 0
13.252602 ABIN5619509 WB Rabbit Center Log in to see Polyclonal 0
13.252602 ABIN636307 WB Rabbit IgG AA 280-296 Log in to see Polyclonal 0
13.252602 ABIN2153446 ELISA WB Rabbit IgG Log in to see Polyclonal 0
12.303753 ABIN3044205 IHC (p) WB Rabbit IgG AA 333-348, C-Term Log in to see Polyclonal 2
12.303753 ABIN6265635 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 1
12.303753 ABIN1030367 ICC ELISA WB Rabbit C-Term Log in to see Polyclonal 2
12.303753 ABIN542655 FACS WB Rabbit Log in to see Polyclonal 3
10.803753 ABIN395528 ELISA IP WB Mouse IgG1 kappa AA 71-170 Log in to see 2D6 0
10.803753 ABIN522238 IP WB Rabbit AA 1-440 Log in to see Polyclonal 0
10.803753 ABIN522239 IP WB Rabbit AA 1-440 Log in to see Polyclonal 0

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Epitope AA 233-440
(42), (14), (13), (10), (10), (9), (8), (8), (8), (8), (7), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(315), (68), (28), (1), (1), (1), (1), (1)
Host Rabbit
(186), (158), (8), (6), (2)
Clonality
Polyclonal
Conjugate This TNFRSF10B antibody is un-conjugated
(19), (18), (16), (6), (5), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(201), (133), (76), (61), (40), (35), (30), (27), (16), (13), (13), (8), (3), (3), (3), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B antibody (ABIN5518794) Images
Purpose Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 10B(TNFRSF10B) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 10B(TNFRSF10B) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: tumor necrosis factor receptor superfamily, member 10b
Protein Name: Tumor necrosis factor receptor superfamily member 10B
Purification Immunogen affinity purified.
Immunogen E.coli-derived human DR5 recombinant protein (Position: K233-S440). Human DR5 shares 48.4% amino acid (aa) sequence identity with mouse DR5.
Isotype IgG
Plasmids, Primers & others

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling References for anti-TNFRSF10B antibody (ABIN5518794) Images back to top
Antigen
Alternative Name TNFRSF10B (TNFRSF10B Antibody Abstract)
Background TNFRSF10B(Tumor necrosis factor receptor superfamily, member 10b) is a human gene. It is also known as DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9, TRAILR2, TRICK2A, TRICK2B, TRAIL-R2, KILLER/DR5. The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Mice have a homologous gene, tnfrsf10b that has been essential in the elucidation of the function of this gene in humans. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.By analysis of radiation hybrid panels, this gene is mapped to chromosome 8p22-p21. Northern blot analysis indicated that TRAILR2 was expressed as a 4.4-kb mRNA in all tissues tested, with the highest levels of expression in peripheral blood lymphocytes, spleen, and ovary.

Synonyms: CD262 antigen | Cytotoxic TRAIL receptor 2 | DR5 | Dr5 | Killer | KILLER | O14763 | TNFRSF10B | TR10B | trail r2 | trailr 2 | TRAILR2 | TRAIL-R2 | TRICK2 | TRICK2A | TRICK2B
Gene ID 8795
UniProt O14763
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling References for anti-TNFRSF10B antibody (ABIN5518794) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details References for anti-TNFRSF10B antibody (ABIN5518794) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-TNFRSF10B antibody (ABIN5518794)

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling Images back to top
Product cited in:

Liu, Zuo, Wang, Chen, Yang, Wang, Zhu: "miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT." in: Oncotarget, Vol. 5, Issue 13, pp. 4959-71, 2014

Images

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B antibody (ABIN5518794) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 233-440) antibody (ABIN5518794) DR5 was detected in paraffin-embedded sections of human intetsinal cancer tissues usi...
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 233-440) antibody (ABIN5518794) DR5 was detected in paraffin-embedded sections of mouse intestine tissues using rabbi...
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 233-440) antibody (ABIN5518794) DR5 was detected in paraffin-embedded sections of rat kidney tissues using rabbit ant...
Western Blotting (WB) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 233-440) antibody (ABIN5518794) Western blot analysis of DR5 expression in rat thymus extract ( Lane 1), mouse cardia...