anti-Human TNFRSF10B antibody for Western Blotting

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor superfamily member 10b S homeolog
  • tumor necrosis factor receptor superfamily member 10b L homeolog
  • tumor necrosis factor receptor superfamily member 10b
  • TNF receptor superfamily member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b.S
  • tnfrsf10b.L
  • tnfrsf10b
Epitope
AA 333-348, C-Term
43
17
14
12
10
10
9
9
8
8
8
5
5
5
5
4
4
4
4
4
4
3
3
3
3
3
2
1
1
1
1
1
1
1
Reactivity
Human
322
77
27
1
1
1
1
1
Host
Rabbit
178
169
10
6
6
2
Clonality
Polyclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
23
20
16
8
6
5
5
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
192
163
72
52
39
32
27
23
16
16
13
4
4
3
3
2
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN3044205
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2563753 ABIN222914 WB Rabbit IgG Log in to see Polyclonal 1
3.2563753 ABIN2792103 WB Rabbit N-Term Log in to see Polyclonal 1
3.2563753 ABIN2706057 WB Rabbit Center Log in to see Polyclonal 0
3.2563753 ABIN4361766 FACS ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal 37
3.2563753 ABIN2855397 WB Rabbit IgG Center Log in to see Polyclonal 0
3.2563753 ABIN1980532 ICC IHC WB Rabbit IgG AA 234-435 Log in to see Polyclonal 0
3.2563753 ABIN1875126 IHC WB Rabbit IgG Log in to see Polyclonal 0
3.2563753 ABIN1030367 ICC ELISA WB Rabbit C-Term Log in to see Polyclonal 2
3.2563753 ABIN151173 ICC IF IHC (fro) WB Rabbit Log in to see Polyclonal 0
3.2563753 ABIN522238 IP WB Rabbit AA 1-440, full length Log in to see Polyclonal 0
3.2563753 ABIN2479551 IHC (fro) WB Rabbit IgG AA 388-407 Log in to see Polyclonal 1
3.2563753 ABIN4903511 ICC WB Mouse IgG Log in to see 0
3.2563753 ABIN522239 IP WB Rabbit AA 1-440, full length Log in to see Polyclonal 0
3.2563753 ABIN522237 WB Mouse AA 1-440, full length Log in to see Polyclonal 0
3.2563753 ABIN3021808 IHC WB Rabbit IgG Log in to see Polyclonal 0
3.2563753 ABIN1583640 ELISA ICC IF WB Rabbit Log in to see Polyclonal 0
3.2563753 ABIN926857 WB Rabbit N-Term Log in to see Polyclonal 0
3.2563753 ABIN187721 WB Rabbit AA 388-407 Log in to see Polyclonal 0
3.2563753 ABIN4248952 WB Rabbit AA 280-296 Log in to see Polyclonal 0
3.2563753 ABIN4248951 WB Rabbit AA 380-398 Log in to see Polyclonal 0

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Epitope AA 333-348, C-Term
(43), (17), (14), (12), (10), (10), (9), (9), (8), (8), (8), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(322), (77), (27), (1), (1), (1), (1), (1)
Host Rabbit
(178), (169), (10), (6), (6), (2)
Clonality
Polyclonal
Conjugate This TNFRSF10B antibody is un-conjugated
(23), (20), (16), (8), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(192), (163), (72), (52), (39), (32), (27), (23), (16), (16), (13), (4), (4), (3), (3), (2), (1), (1)
Pubmed 2 references available
Supplier Log in to see

Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B antibody (ABIN3044205) Images
Purpose Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 10B(TNFRSF10B) detection. Tested with WB, IHC-P in Human.
Sequence DPTETLRQCF DDFADL
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 10B(TNFRSF10B) detection. Tested with WB, IHC-P in Human.
Gene Name: tumor necrosis factor receptor superfamily, member 10b
Protein Name: Tumor necrosis factor receptor superfamily member 10B
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human DR5(333-348aa DPTETLRQCFDDFADL).
Isotype IgG

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling References for anti-TNFRSF10B antibody (ABIN3044205) Images back to top
Antigen
Alternative Name TNFRSF10B (TNFRSF10B Antibody Abstract)
Background TNFRSF10B(Tumor necrosis factor receptor superfamily, member 10b) is a human gene. It is also known as DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9, TRAILR2, TRICK2A, TRICK2B, TRAIL-R2, KILLER/DR5. The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand(TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Mice have a homologous gene, tnfrsf10b, that has been essential in the elucidation of the function of this gene in humans. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.By analysis of radiation hybrid panels, Walczak et al.(1997) mapped the TRAILR2 gene to chromosome 8p22-p21. Northern blot analysis indicated that TRAILR2 was expressed as a 4.4-kb mRNA in all tissues tested, with the highest levels of expression in peripheral blood lymphocytes, spleen, and ovary.

Synonyms: Fas like protein antibody|Apoptosis inducing protein TRICK2A/2B antibody|Apoptosis inducing receptor TRAIL R2 antibody|CD262 antibody|CD262 antigen antibody|Cytotoxic TRAIL receptor 2 antibody|Death domain containing receptor for TRAIL/Apo 2L antibody|Death receptor 5 antibody|DR5 antibody|KILLER antibody|KILLER/DR5 antibody|OTTHUMP00000123492 antibody|OTTHUMP00000123493 antibody|p53 regulated DNA damage inducible cell death receptor(killer) antibody|TNF related apoptosis inducing ligand receptor 2 antibody|TNF-related apoptosis-inducing ligand receptor 2 antibody|TNFRSF10B antibody|TR10B_HUMAN antibody|TRAIL R2 antibody|TRAIL receptor 2 antibody|TRAIL-R2 antibody|TRAILR2 antibody|TRICK2 antibody|TRICK2A antibody|TRICK2B antibody|TRICKB antibody|Tumor necrosis factor receptor like protein ZTNFR9 antibody|Tumor necrosis factor receptor superfamily member 10B antibody|Tumor necrosis factor receptor superfamily, member 10b antibody|ZTNFR9 antibody
UniProt O14763
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling References for anti-TNFRSF10B antibody (ABIN3044205) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details References for anti-TNFRSF10B antibody (ABIN3044205) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Expiry Date 12 months

References for anti-TNFRSF10B antibody (ABIN3044205)

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling Images back to top
Product cited in:

Liu, Zuo, Wang, Chen, Yang, Wang, Zhu: "miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT." in: Oncotarget, Vol. 5, Issue 13, pp. 4959-71, 2014

Li, Shen, Peng, Chen, Jiang, Li, Zhang, Lu: "Plumbagin enhances TRAIL-mediated apoptosis through up-regulation of death receptor in human melanoma A375 cells." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 30, Issue 4, pp. 458-63, 2010

Images

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B antibody (ABIN3044205) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 333-348), (C-Term) antibody (ABIN3044205) Anti-DR5 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue
Western Blotting (WB) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 333-348), (C-Term) antibody (ABIN3044205) Anti-DR5 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: MM231 Cell Lysat...