anti-Mouse (Murine) TNFRSF10B antibody for ELISA (Capture)

Recommended TNFRSF10B Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor superfamily member 10b S homeolog
  • tumor necrosis factor receptor superfamily member 10b L homeolog
  • tumor necrosis factor receptor superfamily member 10b
  • TNF receptor superfamily member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b.S
  • tnfrsf10b.L
  • tnfrsf10b
Reactivity
Mouse (Murine)
303
68
29
2
1
1
1
1
Host
Hamster
183
148
8
5
2
Clonality
Monoclonal
Conjugate
This TNFRSF10B antibody is conjugated to Biotin
18
18
16
6
5
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA (Capture), Intracellular Flow Cytometry (ICFC), Immunohistochemistry (IHC), Western Blotting (WB)
198
131
68
61
39
35
30
27
14
13
13
8
3
3
2
2
1
Supplier
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Pubmed
6 references available
Catalog No. ABIN2661014
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General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) Antibodies
Reactivity Mouse (Murine)
(303), (68), (29), (2), (1), (1), (1), (1)
Host Hamster
(183), (148), (8), (5), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF10B antibody is conjugated to Biotin
(18), (18), (16), (6), (5), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA (Capture), Intracellular Flow Cytometry (ICFC), Immunohistochemistry (IHC), Western Blotting (WB)
(198), (131), (68), (61), (39), (35), (30), (27), (14), (13), (13), (8), (3), (3), (2), (2), (1)
Pubmed 6 references available
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Product Details anti-TNFRSF10B Antibody

Target Details TNFRSF10B Application Details Handling References for anti-TNFRSF10B antibody (ABIN2661014) Images
Purification The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone MD5-1
Isotype IgG
Plasmids, Primers & others

Target Details TNFRSF10B

Product Details anti-TNFRSF10B Antibody Application Details Handling References for anti-TNFRSF10B antibody (ABIN2661014) Images back to top
Antigen
Alternative Name CD262 (TNFRSF10B Antibody Abstract)
Background CD262 is a 55 kD protein also known as DR5, TRAIL-R2, Apo-2, TRICK2, and KILLER. DR5 is member 10B of the TNF receptor superfamily (TNFRSF10B), widely expressed in normal tissues and some tumor cell lines. The DR5 receptor binds to TRAIL and interacts with the cytoplasmic proteins TRADD and RIP. TRAIL binding to DR5 activates NF- κB and induces apoptosis. DR5 is induced by wild-type p53.
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Handling References for anti-TNFRSF10B antibody (ABIN2661014) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details References for anti-TNFRSF10B antibody (ABIN2661014) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-TNFRSF10B antibody (ABIN2661014)

Product Details anti-TNFRSF10B Antibody Target Details TNFRSF10B Application Details Handling Images back to top
Background publications

Grisendi, Bussolari, Cafarelli, Petak, Rasini, Veronesi, De Santis, Spano, Tagliazzucchi, Barti-Juhasz, Scarabelli, Bambi, Frassoldati, Rossi, Casali, Morandi, Horwitz, Paolucci, Conte, Dominici: "Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy." in: Cancer research, Vol. 70, Issue 9, pp. 3718-29, 2010

Iannello, Samarani, Debbeche, Ahmad, Boulassel, Tremblay, Toma, Routy, Ahmad: "Potential role of interleukin-18 in the immunopathogenesis of AIDS: involvement in fratricidal killing of NK cells." in: Journal of virology, Vol. 83, Issue 12, pp. 5999-6010, 2009

Sato, Nakaoka, Yamashita, Yagita, Kawasaki, Morimoto, Baba, Matsuyama: "TRAIL-transduced dendritic cells protect mice from acute graft-versus-host disease and leukemia relapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 7, pp. 4025-33, 2005

Takeda, Yamaguchi, Akiba, Kojima, Hayakawa, Tanner, Sayers, Seki, Okumura, Yagita, Smyth: "Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy." in: The Journal of experimental medicine, Vol. 199, Issue 4, pp. 437-48, 2004

Hayakawa, Screpanti, Yagita, Grandien, Ljunggren, Smyth, Chambers: "NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 1, pp. 123-9, 2003

Wu, Burns, Zhan, Alnemri, El-Deiry: "Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor." in: Cancer research, Vol. 59, Issue 12, pp. 2770-5, 1999