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PDE4D Products

(phosphodiesterase 4D, cAMP-Specific (PDE4D))
The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010].

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Featured PDE4D Categories

PDE4D Antibodies

High quality antibodies with extensive validation data.

PDE4D ELISA Kits

Reliable ELISA kits for a wide range of species.

PDE4D Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PDE4D Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, EIA
Validations
  • (1)
  • (4)
Cat. No. ABIN185530
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (3)
Cat. No. ABIN2855885
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Horse, Human, Monkey, Mouse, Pig, Rat, Xenopus laevis
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6749764
Quantity 100 μL
Datasheet Datasheet

Recommended PDE4D ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969263
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958534
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380247
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended PDE4D Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1782353
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314469
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3085805
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PDE4D products

Cao, Wang, Liao, Zhou, Liao, Zeng, He, Chen, He, Li, Lu: "Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation." in: eLife, Vol. 5, (2016) (PubMed).

Massimi, Cardarelli, Galli, Giardi, Ragusa, Panera, Cinque, Cifone, Biagioni, Giorgi: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Guo, Lin, Zhao, Zhang, Wei, Wang, Wang: "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." in: Neuroscience, Vol. 263, pp. 1-14, (2014) (PubMed).

Zhai, Chang, Wei, Liu, Leblais, Fischmeister, Ji: "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." in: Cellular signalling, Vol. 26, Issue 5, pp. 1001-10, (2014) (PubMed).

Dong, Guo, Ye, Hare: "Presynaptic inhibition by α2 receptor/adenylate cyclase/PDE4 complex at retinal rod bipolar synapse." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 28, pp. 9432-40, (2014) (PubMed).

Wang, Zhang, Liu, Zhao, Zhang, Yuan, An, Li, Wang, Qin, Wilson, ODonnell, Zhang, Li: "RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects." in: British journal of pharmacology, Vol. 168, Issue 4, pp. 1001-14, (2013) (PubMed).

Michalski, Kanaji, Liu, Nogel, Wang, Basma, Nakanishi, Sato, Gunji, Fahrid, Nelson, Muller, Holz, Magnussen, Rabe, Toews, Rennard: "Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4." in: American journal of respiratory cell and molecular biology, Vol. 47, Issue 6, pp. 729-37, (2013) (PubMed).

Al-Tawashi, Jung, Liu, Su, Qin: "Protein implicated in nonsyndromic mental retardation regulates protein kinase A (PKA) activity." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 14644-58, (2012) (PubMed).

Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

Synonyms and alternative names related to PDE4D

phosphodiesterase 4D (PDE4D), phosphodiesterase 4D interacting protein (PDE4DIP), phosphodiesterase 4D (pde4d), phosphodiesterase 4D interacting protein (Pde4dip), phosphodiesterase 4D, cAMP specific (Pde4d), phosphodiesterase 4D (Pde4d), phosphodiesterase 4D, cAMP-specific (Pde4d), phosphodiesterase 4D interacting protein (myomegalin) (Pde4dip), phosphodiesterase 4D, cAMP-specific (pde4d), 4732458A06Rik, 9430063L05Rik, 9630011N22Rik, ACRDYS2, C87016, CMYA2, D3Bwg1078e, D130016K21Rik, DPDE3, Dpde3, HSPDE4D, mKIAA0454, MMGL, PDE4DN2, PDE43, si:dkey-190g11.2, STRK1, Usmg4

Protein level used designations for PDE4D

  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • cAMP-specific phosphodiesterase PDE4D6
  • phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)
  • cardiomyopathy-associated protein 2
  • myomegalin
  • phosphodiesterase 4D, cAMP-specific
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like
  • phosphodiesterase 4D-interacting protein
  • phosphodiesterase-binding protein clone 46
  • cAMP-specific phosphodiesterase 4D
  • cyclic AMP specific phosphodiesterase PDE4D5A
  • dunce
  • DPDE3
  • Phosphodiesterase 4D cAMP-specific (dunce
  • Phosphodiesterase 4D, cAMP-specific (dunce
  • cAMP-specific phosphodiesterase PDE4D
  • cAMP-specific phosphodiesterase splice variant PDE4D8
  • phosphodiesterase 4D, cAMP specific
  • hypothetical protein
  • phosphodiesterase E3 dunce homolog, Drosophila
  • upregulated during skeletal muscle growth 4
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