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PDE6B Products

(phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))

Categories

Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].

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Featured PDE6B Categories

PDE6B Antibodies

High quality antibodies with extensive validation data.

PDE6B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PDE6B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN6145363
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (2)
Cat. No. ABIN7262851
Quantity 200 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN2789554
Quantity 100 μL
Datasheet Datasheet

Recommended PDE6B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231751
Quantity 96 tests
Datasheet Datasheet

Recommended PDE6B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3085622
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133360
Quantity 1 mg
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Pig, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750996
Quantity 5 applications
Datasheet Datasheet

Latest Publications for our PDE6B products

Dong, Claffey, Brocke, Epstein: "Expression of phosphodiesterase 6 (PDE6) in human breast cancer cells." in: SpringerPlus, Vol. 2, pp. 680, (2014) (PubMed).

Nikolova, Guenther, Savai, Weissmann, Ghofrani, Konigshoff, Eickelberg, Klepetko, Voswinckel, Seeger, Grimminger, Schermuly, Pullamsetti: "Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis." in: Respiratory research, Vol. 11, pp. 146, (2011) (PubMed).

Synonyms and alternative names related to PDE6B

phosphodiesterase 6B (PDE6B), phosphodiesterase 6B (Pde6b), phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide (Pde6b), CSNB3, CSNBAD2, PDBS, PDEB, Pdeb, r, RCD-1, rd, rd-1, rd1, rd10, RP40

Protein level used designations for PDE6B

  • GMP-PDE beta
  • rod cGMP-phosphodiesterase beta-subunit
  • rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
  • pde6B gene for cGMP phosphodiesterase beta subunit
  • phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal dominant)
  • rod cGMP phosphodiesterase beta subunit
  • phosphodiesterase, cyclic GMP ( rod receptor), beta polypeptide
  • phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
  • cGMP-phosphodiesterase beta-subunit
  • phosphodiesterase, cGMP, rod receptor, beta polypeptide
  • retinal degeneration 1
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