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Selectin E/CD62e Protein (AA 22-556) (His tag)

SELE Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1880739
  • Target See all Selectin E/CD62e (SELE) Proteins
    Selectin E/CD62e (SELE) (Selectin E (SELE))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-556
    Origin
    • 16
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 16
    • 15
    • 5
    • 4
    • 3
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This Selectin E/CD62e protein is labelled with His tag.
    Purpose
    Recombinant Human E-Selectin//ELAM1/CD62E (C-6His)
    Sequence
    WSYNTSTEAM TYDEASAYCQ QRYTHLVAIQ NKEEIEYLNS ILSYSPSYYW IGIRKVNNVW VWVGTQKPLT EEAKNWAPGE PNNRQKDEDC VEIYIKREKD VGMWNDERCS KKKLALCYTA ACTNTSCSGH GECVETINNY TCKCDPGFSG LKCEQIVNCT ALESPEHGSL VCSHPLGNFS YNSSCSISCD RGYLPSSMET MQCMSSGEWS APIPACNVVE CDAVTNPANG FVECFQNPGS FPWNTTCTFD CEEGFELMGA QSLQCTSSGN WDNEKPTCKA VTCRAVRQPQ NGSVRCSHSP AGEFTFKSSC NFTCEEGFML QGPAQVECTT QGQWTQQIPV CEAFQCTALS NPERGYMNCL PSASGSFRYG SSCEFSCEQG FVLKGSKRLQ CGPTGEWDNE KPTCEAVRCD AVHQPPKGLV RCAHSPIGEF TYKSSCAFSC EEGFELHGST QLECTSQGQW TEEVPSCQVV KCSSLAVPGK INMSCSGEPV FGTVCKFACP EGWTLNGSAA RTCGATGHWS GLLPTCEAPT ESNIPVDHHH HHH
    Characteristics
    Recombinant Human E-selectin/ sele is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Trp22-Pro556) of Human E-selectin fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product SELE Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, 4 % Mannitol, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    Selectin E/CD62e (SELE) (Selectin E (SELE))
    Alternative Name
    E-Selectin/ Sele (SELE Products)
    Synonyms
    SELE Protein, CD62E Protein, ELAM Protein, ELAM1 Protein, ESEL Protein, LECAM2 Protein, E-selectin Protein, Elam Protein, selectin E Protein, selectin, endothelial cell Protein, SELE Protein, Sele Protein
    Sub Type
    Fusionprotein
    Background
    SELE is expressed on the surface of endothelial cells and mediates the interaction of leukocytes and platelets with endothelial cells during an inflammatory response. SELE functions as a cell-surface glycoprotein and has a role in immunoadhesion. In addition, SELE may also have a role in capillary morphogenesis.
    Alternative Names: E-selectin (SELE), also known as CD62 antigen-like family member E, Endothelial leukocyte adhesion molecule 1, Leukocyte-endothelial cell adhesion molecule 2, CD62E and ELAM1, is a single-pass type I membrane protein which belongs to the selectin/LECAM fa
    Molecular Weight
    58.6 kDa
    UniProt
    P16581
    Pathways
    Thromboxane A2 Receptor Signaling
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