|Antigen||Cyclin-Dependent Kinase 2 (CDK2) Antibodies|
|Reactivity||Human, Mouse (Murine), Xenopus laevis Alternatives|
|Conjugate||This CDK2 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
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Product Details anti-CDK2 AntibodyTarget Details CDK2 Application Details Handling Images
|Specificity||Recognizes Human CDK2 (MW 33 kDa). Does not cross-react with other CDKs.|
Species reactivity (expected):Xenopus and Mouse.
Species reactivity (tested):Human.
|Characteristics||Synonyms: p33 protein kinase, Cell division protein kinase 2, Cyclin dependent kinase 2|
|Purification||Protein G Chromatography|
|Immunogen||Recombinant Human CDK2.|
Target Details CDK2Product Details anti-CDK2 Antibody Application Details Handling Images back to top
|Alternative Name||CDK2 (CDK2 Antibody Abstract)|
|Background||Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase|
|Pathways||PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA|
Application DetailsProduct Details anti-CDK2 Antibody Target Details CDK2 Handling Images back to top
ELISA. Western blot. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
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|Buffer||0.1 M Tris-glycine, pH 7.4, 150 mM Sodium Chloride, 0.05 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
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