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PRG2 Products

(Bone Marrow Proteoglycan (PRG2))
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

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Featured PRG2 Categories

PRG2 Antibodies

High quality antibodies with extensive validation data.

PRG2 ELISA Kits

Reliable ELISA kits for a wide range of species.

PRG2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRG2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, ICC, IF, IHC, WB
Validations
  • (2)
Cat. No. ABIN6264418
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7145674
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN519158
Quantity 50 μg
Datasheet Datasheet

Recommended PRG2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965181
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975292
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975668
Quantity 96 tests
Datasheet Datasheet

Recommended PRG2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3086419
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3086418
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3123088
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PRG2 products

Singh, Chand, Banerjee, Agarwal, Raizada, Roy, Sopori: "Acetylcholinesterase Inhibitor Pyridostigmine Bromide Attenuates Gut Pathology and Bacterial Dysbiosis in a Murine Model of Ulcerative Colitis." in: Digestive diseases and sciences, Vol. 65, Issue 1, pp. 141-149, (2020) (PubMed).

Roy, Ehrbar, Bohorova, Bohorov, Kim, Pauly, Whaley, Rong, Torres-Velez, Vitetta, Didier, Doyle-Meyers, Zeitlin, Mantis: "Rescue of rhesus macaques from the lethality of aerosolized ricin toxin." in: JCI insight, Vol. 4, Issue 1, (2019) (PubMed).

Hashimoto, Kursewicz, Fayne, Nanda, Shah, Nattkemper, Yokozeki, Yosipovitch: "Pathophysiological mechanisms of itch in bullous pemphigoid." in: Journal of the American Academy of Dermatology, (2019) (PubMed).

Hashimoto, Kursewicz, Fayne, Nanda, Shah, Nattkemper, Yokozeki, Yosipovitch: "Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages." in: The Journal of investigative dermatology, (2019) (PubMed).

Ziemka-Nalecz, Janowska, Strojek, Jaworska, Zalewska, Frontczak-Baniewicz, Sypecka: "Impact of neonatal hypoxia-ischaemia on oligodendrocyte survival, maturation and myelinating potential." in: Journal of cellular and molecular medicine, Vol. 22, Issue 1, pp. 207-222, (2018) (PubMed).

Costa, Trivellato, Rebech, Oliveira Dos Santos Maciel, Melo, Luvizotto, de Lima: "Eosinophilic inflammation in lymph nodes of dogs with visceral leishmaniasis." in: Parasite immunology, Vol. 40, Issue 8, pp. e12567, (2018) (PubMed).

Gormley, Ona, Kapidzic, Garrido-Gomez, Zdravkovic, Fisher: "Preeclampsia: novel insights from global RNA profiling of trophoblast subpopulations." in: American journal of obstetrics and gynecology, Vol. 217, Issue 2, pp. 200.e1-200.e17, (2017) (PubMed).

Bleyer, Curths, Dahlmann, Wichmann, Bauer, Moritz, Braun, Knauf, Kaup, Gruber-Dujardin: "Morphology and staining behavior of neutrophilic and eosinophilic granulocytes of the common marmoset (Callithrix jacchus)." in: Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, (2016) (PubMed).

Vanheel, Vicario, Vanuytsel, Van Oudenhove, Martinez, Keita, Pardon, Santos, Söderholm, Tack, Farré: "Impaired duodenal mucosal integrity and low-grade inflammation in functional dyspepsia." in: Gut, Vol. 63, Issue 2, pp. 262-71, (2014) (PubMed).

Synonyms and alternative names related to PRG2

proteoglycan 2, bone marrow (Prg2), proteoglycan 2 (Prg2), proteoglycan 2, pro eosinophil major basic protein (PRG2), BMPG, MBP, MBP1, mMBP, mMBP-1

Protein level used designations for PRG2

  • BMPG
  • bone marrow proteoglycan
  • major basic protein 1
  • eosinophil major basic protein
  • bone-marrow proteoglycan
  • eosinophil granule major basic protein
  • natural killer cell activator
  • proteoglycan 2 preproprotein
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