CD147 Protein (AA 22-205) (His tag)

Catalog No. ABIN1096561

Product Details

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Protein Type: Recombinant

Protein Characteristics: AA 22-205

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This CD147 protein is labelled with His tag.

Purpose: Recombinant Human EMMPRIN/Basigin/CD147 (C-6His)

Sequence: AAGTVFTTVE DLGSKILLTC SLNDSATEVT GHRWLKGGVV LKEDALPGQK TEFKVDSDDQ WGEYSCVFLP EPMGTANIQL HGPPRVKAVK SSEHINEGET AMLVCKSESV PPVTDWAWYK ITDSEDKALM NGSESRFFVS SSQGRSELHI ENLNMEADPG QYRCNGTSSK GSDQAIITLR VRSHVDHHHH HH

Characteristics: Recombinant Human Extracellular Matrix Metalloproteinase Inducer/EMMPRIN produced by transfected human cells is a secreted protein with sequence (A22-H205) of the extracellular domain with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Alternative Name: emmprin (BSG Products)

Synonyms: EMMPRIN Protein, RPE7 Protein, 5F7 Protein, CD147 Protein, M6 Protein, OK Protein, TCSF Protein, AI115436 Protein, AI325119 Protein, HT-7 Protein, 5A11 Protein, CE9 Protein, HT7 Protein, Ox47R Protein, basignin Protein, wu:fb26a05 Protein, wu:fo98e12 Protein, bsg Protein, prso03 Protein, basigin (Ok blood group) Protein, basigin Protein, basigin (Ok blood group) S homeolog Protein, BSG Protein, Bsg Protein, bsg Protein, bsg.S Protein

Sub Type: Fusionprotein

Background: Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion, metastasis, growth, and survival of malignants cells, serves as a receptor for extracellular cyclophilinthe, may play a role in signal transduction.
Alternative Names: Basigin, 5F7, Collagenase Stimulatory Factor, Extracellular Matrix Metalloproteinase Inducer, EMMPRIN, Leukocyte Activation Antigen M6, OK Blood Group Antigen, Tumor Cell-Derived Collagenase Stimulatory Factor, TCSF, CD147, BSG

Molecular Weight: 21.16 kDa

Pathways: S100 Proteins