ANGPTL7 Protein (AA 1-346) (DYKDDDDK Tag)
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- Target See all ANGPTL7 Proteins
- ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 1-346
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ANGPTL7 protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human ANGPTL7 (aa 1-346) is fused at the C-terminus to a FLAG®-tag.
- Purity
- >90 % (SDS-PAGE)
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product ANGPTL7 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Activates ERK phosphorylation in THP-1 cells.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Expiry Date
- 3 months
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- Target
- ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))
- Alternative Name
- ANGPTL7 (ANGPTL7 Products)
- Synonyms
- AngX Protein, CDT6 Protein, RP4-647M16.2 Protein, dJ647M16.1 Protein, MGC84421 Protein, zgc:101687 Protein, angiopoietin like 7 Protein, angiopoietin-like 7 Protein, angiopoietin like 7 S homeolog Protein, ANGPTL7 Protein, Angptl7 Protein, angptl7.S Protein, angptl7 Protein
- Background
- ANGPTL7 (Angiopoietin-like protein 7) is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.
- Molecular Weight
- ~45kDa (SDS-PAGE)
- UniProt
- O43827
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