NGFB Protein
NGFB
Origin: Mouse
Host: Mouse
Native
> 95 % by SDS-PAGE
Active
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- Target See all NGFB Proteins
- NGFB (Nerve Growth Factor beta (NGFB))
- Protein Type
- Native
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Mouse
- Purity
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product NGFB Protein
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Nerve Growth Factor beta (NGFB) (Active) protein
NGFB Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with sterile 18 mΩ/cm^3 H2O.
- Buffer
- 10 mM Phosphate buffer and 200 mM NaCl (pH 7.0)
- Preservative
- Without preservative
- Storage
- 4 °C
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- Target
- NGFB (Nerve Growth Factor beta (NGFB))
- Alternative Name
- NGF beta (NGFB Products)
- Synonyms
- NGFB Protein, ngfb Protein, ns:zft386 Protein, xx:zft386 Protein, zgc:109730 Protein, hsan5 Protein, beta-ngf Protein, Ngfb Protein, Beta-NGF Protein, HSAN5 Protein, beta-NGF Protein, nerve growth factor Protein, nerve growth factor b (beta polypeptide) Protein, beta-Nerve growth factor Protein, nerve growth factor (beta polypeptide) Protein, NGF Protein, ngfb Protein, FPV072 Protein, FPV076 Protein, ngf Protein, Ngf Protein
- Background
- Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF consists of 3 types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight complex. It is mainly expressed in Sertoli and interstitial cells. The proforms of NGF are secreted and cleaved extracellularly by the serine protease plasmin and by selective matrix metalloproteinases. NGF is important for the growth, maintenance, and survival of certain target neurons (nerve cells). It also functions as a signaling molecule.
- Molecular Weight
- 26.5 kDa
- Pathways
- NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size
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