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HLA-E Protein (AA 1-358) (GST tag)

HLA-E Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Catalog No. ABIN1989653
  • Target See all HLA-E Proteins
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-358
    Origin
    • 6
    • 1
    Human
    Source
    • 4
    • 1
    • 1
    • 1
    Wheat germ
    Purification tag / Conjugate
    This HLA-E protein is labelled with GST tag.
    Application
    Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
    Purpose
    HLA-E (Human) Recombinant Protein (P01)
    Sequence
    MVDGTLLLLL SEALALTQTW AGSHSLKYFH TSVSRPGRGE PRFISVGYVD DTQFVRFDND AASPRMVPRA PWMEQEGSEY WDRETRSARD TAQIFRVNLR TLRGYYNQSE AGSHTLQWMH GCELGPDRRF LRGYEQFAYD GKDYLTLNED LRSWTAVDTA AQISEQKSND ASEAEHQRAY LEDTCVEWLH KYLEKGKETL LHLEPPKTHV THHPISDHEA TLRCWALGFY PAEITLTWQQ DGEGHTQDTE LVETRPAGDG TFQKWAAVVV PSGEEQRYTC HVQHEGLPEP VTLRWKQASQ PTIPIVGIIA GLVLLGSVVS GAVVAAVIWR KKSSGGKGGS YSKAEWSDSA QGSESHSL
    Characteristics
    Human HLA-E full-length ORF (no protein_acc, 1 a.a. - 358 a.a.) recombinant protein with GST tag at N-terminal.
    Purification
    in vitro wheat germ expression system
    Top Product
    Discover our top product HLA-E Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -80 °C
    Storage Comment
    Best use within three months from the date of receipt of this protein.
  • Target
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    Alternative Name
    HLA-E (HLA-E Products)
    Synonyms
    EA1.2 Protein, EA2.1 Protein, HLA-6.2 Protein, MHC Protein, QA1 Protein, major histocompatibility complex, class I, E Protein, HLA-E Protein, PATR-E Protein
    Background
    Synonyms: DKFZp686P19218,EA1.2,EA2.1,HLA-6.2,MHC,QA1
    Gene Description: major histocompatibility complex, class I, E
    Gene Name: HLA-E
    Gene Summary: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
    GenBank: AK098434.1
    Molecular Weight
    66.6 kDa (theoreatical)
    Gene ID
    3133
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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