IL-13 Protein (AA 22-131) (His tag)
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- Target See all IL-13 (IL13) Proteins
- IL-13 (IL13) (Interleukin 13 (IL13))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 22-131
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Origin
- Mouse
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Source
- CHO Cells
- Purification tag / Conjugate
- This IL-13 protein is labelled with His tag.
- Characteristics
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ED50 < 20 ng /mL, measured in a cell proliferation assay using R&D TF-1 cells.
AA 22-131, expressed with C-terminal 6xHis. - Purity
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL13 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant murine Interleukin-13 (IL-13), His remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, murine Interleukin-13 (IL-13), His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- IL-13 (IL13) (Interleukin 13 (IL13))
- Alternative Name
- Interleukin-13 (IL-13) (IL13 Products)
- Synonyms
- IL13 Protein, IL-13 Protein, P600 Protein, Il-13 Protein, L13 Protein, interleukin 13 Protein, IL13 Protein, Il13 Protein
- Background
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Interleukin-13 (IL-13), also known as T-cell activation protein P600, is an immunoregulatory cytokine belonging to the IL-4/IL-13 family. It is produced by activated Th2 cells, mast cells and NK cells. IL-13 signals through a receptor complex composed of IL-4R alpha and IL13Ralpha1 (or IL13Ralpha2). IL-13 inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha and IL-6 by monocytes and macrophages. It also induces B cell activation and IgE secretion.
Synonyms: NC300 (Human) P600 (Murine) - Molecular Weight
- 14-30 kDa, observed by reducing SDS-PAGE.
- UniProt
- P20109
- Pathways
- JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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