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IL-13 Protein (AA 22-131) (His tag)

IL13 Origin: Mouse Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2018063
  • Target See all IL-13 (IL13) Proteins
    IL-13 (IL13) (Interleukin 13 (IL13))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 22-131
    Origin
    • 24
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Source
    • 26
    • 16
    • 8
    • 7
    • 2
    • 1
    • 1
    CHO Cells
    Purification tag / Conjugate
    This IL-13 protein is labelled with His tag.
    Characteristics
    ED50 < 20 ng /mL, measured in a cell proliferation assay using R&D TF-1 cells.
    AA 22-131, expressed with C-terminal 6xHis.
    Purity
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product IL13 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant murine Interleukin-13 (IL-13), His remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, murine Interleukin-13 (IL-13), His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    IL-13 (IL13) (Interleukin 13 (IL13))
    Alternative Name
    Interleukin-13 (IL-13) (IL13 Products)
    Synonyms
    IL13 Protein, IL-13 Protein, P600 Protein, Il-13 Protein, L13 Protein, interleukin 13 Protein, IL13 Protein, Il13 Protein
    Background
    Interleukin-13 (IL-13), also known as T-cell activation protein P600, is an immunoregulatory cytokine belonging to the IL-4/IL-13 family. It is produced by activated Th2 cells, mast cells and NK cells. IL-13 signals through a receptor complex composed of IL-4R alpha and IL13Ralpha1 (or IL13Ralpha2). IL-13 inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha and IL-6 by monocytes and macrophages. It also induces B cell activation and IgE secretion.
    Synonyms: NC300 (Human) P600 (Murine)
    Molecular Weight
    14-30 kDa, observed by reducing SDS-PAGE.
    UniProt
    P20109
    Pathways
    JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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