Mesothelin Protein (MSLN) (AA 37-286) (His tag)
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- Target See all Mesothelin (MSLN) Proteins
- Mesothelin (MSLN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 37-286
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Mesothelin protein is labelled with His tag.
- Sequence
- AA 37-286
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.6 kDa. The protein migrates as 32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MSLN Protein
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Mesothelin (MSLN) protein (Fc Tag)
MSLN Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Mesothelin (MSLN) protein (Fc-Avi Tag,Biotin)MSLN Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (Fc Tag)MSLN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Mesothelin (MSLN) (AA 296-580) protein (His-Avi Tag)MSLN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) protein (His tag)MSLN Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Mesothelin (MSLN) protein (His-Avi Tag,Biotin)MSLN Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Mesothelin (MSLN) (AA 406-690) protein (His tag,Biotin)MSLN Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) protein (His tag)MSLN Origin: Mouse Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Mesothelin (MSLN) (AA 1-621) protein (GST tag)MSLN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Mesothelin (MSLN) (AA 464-563) protein (GST tag)MSLN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- Mesothelin (MSLN)
- Alternative Name
- Mesothelin (MSLN Products)
- Synonyms
- MPF Protein, SMRP Protein, MSLN Protein, mesothelin Protein, MSLN Protein, Msln Protein, LOC611363 Protein, LOC100524016 Protein
- Background
- Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
- Molecular Weight
- 27.5 kDa
- Pathways
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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