APOE Protein
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- Target See all APOE Proteins
- APOE (Apolipoprotein E (APOE))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Apolipoprotein E / Apo E protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 90 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Top Product
- Discover our top product APOE Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- APOE (Apolipoprotein E (APOE))
- Alternative Name
- Apolipoprotein E,apo E (APOE Products)
- Synonyms
- ad2 Protein, apoprotein Protein, im:7036787 Protein, wu:fb69a05 Protein, zgc:110064 Protein, apoe Protein, AI255918 Protein, AD2 Protein, LDLCQ5 Protein, LPG Protein, APOEA Protein, Apo-E Protein, apolipoprotein E Protein, apolipoprotein Ea Protein, apoe Protein, apoea Protein, Apoe Protein, APOE Protein
- Background
- The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
- Molecular Weight
- 34.3 kDa
- NCBI Accession
- NP_000032
- Pathways
- Regulation of Cell Size, Lipid Metabolism
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