SKP1 Protein (His tag)
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- Target See all SKP1 Proteins
- SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SKP1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SKP1 / OCP2 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SKP1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris,8M Urea, pH 8.0.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
- Alternative Name
- Skp1,ocp2 (SKP1 Products)
- Synonyms
- EMC19 Protein, OCP-II Protein, OCP2 Protein, SKP1A Protein, TCEB1L Protein, p19A Protein, 15kDa Protein, 2610043E24Rik Protein, 2610206H23Rik Protein, SKP1 Protein, Tceb1l Protein, p19Skp1 Protein, Skp1a Protein, skp1a Protein, zgc:73186 Protein, ocp2 Protein, emc19 Protein, ocp-ii Protein, tceb1l Protein, ARABIDOPSIS SKP1 HOMOLOGUE 1 Protein, ASK1 Protein, ATSKP1 Protein, S phase kinase-associated protein 1 Protein, T4O12.17 Protein, T4O12_17 Protein, UFO INTERACTING PROTEIN 1 Protein, UIP1 Protein, ocp-2 Protein, S-phase kinase associated protein 1 Protein, S-phase kinase-associated protein 1 Protein, S-phase kinase-associated protein 1 pseudogene Protein, S-phase kinase-associated protein 1A Protein, S-phase kinase-associated protein 1 S homeolog Protein, S phase kinase-associated protein 1 Protein, SKP1 Protein, skp1 Protein, LOC100340043 Protein, Skp1a Protein, Skp1 Protein, skp1.S Protein
- Background
- This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
- Molecular Weight
- 17.9 kDa
- NCBI Accession
- NP_008861
- Pathways
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases
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