VEGFC Protein (His tag)

Catalog No. ABIN2735229

Product Details

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: CHO Cells

Purification tag / Conjugate: This VEGFC protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)

Specificity: Optimal preservation of protein structure, post-translational modifications and functions.

Characteristics:

• Recombinant human VEGF-C / Flt4-L protein expressed in CHO cells.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Purity: > 98 % , as determined by Coomassie stained SDS-PAGE.

Endotoxin Level: Less than 0.01 ng per μg protein as determined by the LAL method.

Biological Activity Comment: The ED50 is 100 ~ 500 ng/ml, corresponding to a specific activity of 0.2 - 1.0 x 10^4 units/mg, determined by the dose dependent stimulation of HUVEC cell proliferation.

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: > 50 μg/mL

Buffer: 1 x PBS

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Alternative Name: Vegf-C,flt4-L (VEGFC Products)

Synonyms: VEGFC Protein, vegf-c Protein, xvegf-c Protein, Flt4-L Protein, VRP Protein, AW228853 Protein, VEGF-C Protein, vascular endothelial growth factor c Protein, vascular endothelial growth factor C Protein, vascular endothelial growth factor C S homeolog Protein, vegfc Protein, VEGFC Protein, vegfc.S Protein, Vegfc Protein

Background: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors.

Molecular Weight: 15.4 kDa

NCBI Accession: NP_005420

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2