BTN1A1 Protein (AA 27-242) (His tag)
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- Target See all BTN1A1 Proteins
- BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-242
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BTN1A1 protein is labelled with His tag.
- Application
- Functional Studies (Func)
- Sequence
- AA 27-242
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.8 kDa. The protein migrates as 35-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product BTN1A1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))
- Alternative Name
- BTN1A1 (BTN1A1 Products)
- Synonyms
- BT Protein, BTN Protein, Btn Protein, BTN1A1 Protein, TVC Protein, butyrophilin subfamily 1 member A1 Protein, butyrophilin, subfamily 1, member A1 Protein, zgc:162154 Protein, BTN1A1 Protein, Btn1a1 Protein, btn1a1 Protein, zgc:162154 Protein
- Background
- Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
- Molecular Weight
- 25.8 kDa
- Pathways
- Activated T Cell Proliferation
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