PAK1 Protein (AA 248-545)
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- Target See all PAK1 Proteins
- PAK1 (P21-Activated Kinase 1 (PAK1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 248-545
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS), Functional Studies (Func)
- Purpose
- PAK1 (Human) Recombinant Protein
- Sequence
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GPHMSDEEILEKLR SIVSVGDPKK KYTRFEKIGQ GASGTVYTAM DVATGQEVAI KQMNLQQQPK KELIINEILV MRENKNPNIV NYLDSYLVGD ELWVVMEYLA GGSLTDVVTE TCMDEGQIAA VCRECLQALE FLHSNQVIHR DIKSDNILLG MDGSVKLTDF GFCAQITPEQ SKRSTMVGTPYWMAP EVVTRKAYGP KVDIWSLGIM AIEMIEGEPP YLNENPLRAL YLIATNGTPE LQNPEKLSAI FRDFLNRCLE MDVEKRGSAK ELLQHQFLKI AKPLSSLTPL IAAAKEATKN NH
The first 4 residues GPHM are from Turbo3C Protease cleavage site. The underlined T is phosphoryl ated T423. - Characteristics
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Human PAK1 kinase domain (Q13153, 248 a.a. - 545 a.a.) partial recombinant protein expressed in Escherichia coli. The recombinant protein does not have the inhibitory switch domain and has high specific activity.
This product with activity data is belong to bioactive protein. - Purification
- Escherichia coli expression system
- Top Product
- Discover our top product PAK1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Escherichia coli expression system
Product Quality tested by: Loading 8 ug protein in SDS-PAGE - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- In 25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -80 °C
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- Target
- PAK1 (P21-Activated Kinase 1 (PAK1))
- Alternative Name
- PAK1 (PAK1 Products)
- Synonyms
- X-PAK1 Protein, XPak1 Protein, pak Protein, pak-1 Protein, pakalpha Protein, PAKalpha Protein, AW045634 Protein, PAK-1 Protein, Paka Protein, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog Protein, p21 (RAC1) activated kinase 1 Protein, p21 protein (Cdc42/Rac)-activated kinase 1 Protein, Serine/threonine-protein kinase pak-1 Protein, pak1.S Protein, PAK1 Protein, Pak1 Protein, pak-1 Protein
- Background
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Full Gene Name: p21 protein (Cdc42/Rac)-activated kinase 1
Synonyms: MGC130000,MGC130001,PAKalpha - Gene ID
- 5058
- Pathways
- MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
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