Glycoprotein / GP (Virus) (partial) protein (His tag)

Catalog No. ABIN5608208

Product Details

Target: Glycoprotein / GP (Virus)

Protein Type: Recombinant

Protein Characteristics: partial

Origin: Human Herpesvirus 5 (HHV-5), Human respiratory syncytial virus A

Source: HEK-293 Cells

Purification tag / Conjugate: His tag

Application: Western Blotting (WB)

Sequence: His 67 - Arg 297

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Application Details

Application Notes: This recombinant protein can be used for WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C,-80 °C

Storage Comment: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Target Details

Target: Glycoprotein / GP (Virus)

Target Type: Viral Protein

Background: Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. Human respiratory syncytial virus A (strain Long) major surface glycoprotein G (RSV-G), a member of the pneumoviruses glycoprotein G family, is also known as attachment glycoprotein G and membrane-bound glycoprotein (mG), which contains a linear heparin binding domain essential for virus attachment to the host. Concretely speaking, RSV-G can attache the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Furthermore, RSV-G can also interact with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, RSV-G lacks both neuraminidase and hemagglutinating activities.

Molecular Weight: 26.2 kDa

Gene ID: 144411

UniProt: P20895