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CD74 Protein (AA 56-279, Extracellular) (His tag)

CD74 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5709245
  • Target See all CD74 Proteins
    CD74 (HLA-DR-gamma (CD74))
    Protein Type
    Recombinant
    Protein Characteristics
    Extracellular, AA 56-279
    Origin
    • 13
    • 10
    • 3
    Mouse
    Source
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CD74 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    QQQGRLDKLT ITSQNLQLES LRMKLPKSAK PVSQMRMATP LLMRPMSMDN MLLGPVKNVT KYGNMTQDHV MHLLTRSGPL EYPQLKGTFP ENLKHLKNSM DGVNWKIFES WMKQWLLFEM SKNSLEEKKP TEAPPKVLTK CQEEVSHIPA VYPGAFRPKC DENGNYLPLQ CHGSTGYCWC VFPNGTEVPH TKSRGRHNCS EPLDMEDLSS GLGVTRQELG QVTL
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product CD74 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    CD74 (HLA-DR-gamma (CD74))
    Alternative Name
    HG2A (CD74 Products)
    Synonyms
    DHLAG Protein, HLADG Protein, II Protein, Ia-GAMMA Protein, CLIP Protein, Ii Protein, INVG34 Protein, Iclp-1 Protein, iclp1 Protein, wu:fb11f09 Protein, wu:fb12a01 Protein, wu:fb13d06 Protein, wu:fk94e07 Protein, Iclp-2 Protein, cd74 Protein, iclp2 Protein, zgc:123161 Protein, CD74 molecule Protein, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) Protein, CD74 molecule, major histocompatibility complex, class II invariant chain a Protein, CD74 molecule, major histocompatibility complex, class II invariant chain b Protein, CD74 Protein, Cd74 Protein, cd74a Protein, cd74b Protein
    Background
    Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.
    Molecular Weight
    29.5 kDa
    UniProt
    P04441
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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