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BTLA Protein (AA 31-157) (Fc Tag)

BTLA Origin: Human Host: CHO Cells Recombinant >98 % (SDS-PAGE)
Catalog No. ABIN6253355
  • Target See all BTLA Proteins
    BTLA (B and T Lymphocyte Associated (BTLA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 31-157
    Origin
    • 28
    • 12
    • 2
    • 1
    Human
    Source
    • 28
    • 5
    • 5
    • 4
    • 1
    CHO Cells
    Purification tag / Conjugate
    This BTLA protein is labelled with Fc Tag.
    Purpose
    CD272 [BTLA] (human):Fc (human) (rec.)
    Specificity
    The extracellular domain of human CD272 (aa 31-157) is fused to the N-terminus of the Fc region of human IgG1.
    Characteristics
    Protein. The extracellular domain of human CD272 (aa 31-157) is fused to the N-terminus of the Fc region of human IgG1. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). BTLA is a type I transmembrane glycoprotein of the CD28 family of T cell costimulatory molecules. BTLA functions as a coinhibitor on activated T cells and on B cells and dendritic cells. The extracellular domain (ECD) of this Ig superfamily protein contains one V-type Ig-like domain, which interacts with HVEM.
    Purity
    >98 % (SDS-PAGE)
    Endotoxin Level
    <0.06EU/μg protein (LAL test, Lonza).
    Biological Activity Comment
    Measured in a competitive binding assay.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized from 0.2μm-filtered solution in PBS.
    Handling Advice
    Avoid freeze/thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

  • Target
    BTLA (B and T Lymphocyte Associated (BTLA))
    Alternative Name
    CD272 [BTLA] (BTLA Products)
    Synonyms
    BTLA Protein, BTLA1 Protein, CD272 Protein, A630002H24 Protein, B and T lymphocyte associated Protein, BTLA Protein, Btla Protein
    Background

    Alternate Names/Synonyms: BTLA, B- and T-lymphocyte attenuator

    Product Description: BTLA is a type I transmembrane glycoprotein of the CD28 family of T cell costimulatory molecules. BTLA functions as a coinhibitor on activated T cells and on B cells and dendritic cells. The extracellular domain (ECD) of this Ig superfamily protein contains one V-type Ig-like domain, which interacts with HVEM.

    NCBI Accession
    NP_861445
    Pathways
    Cancer Immune Checkpoints
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