BTLA Protein (AA 31-157) (Fc Tag)
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- Target See all BTLA Proteins
- BTLA (B and T Lymphocyte Associated (BTLA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-157
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Origin
- Human
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Source
- CHO Cells
- Purification tag / Conjugate
- This BTLA protein is labelled with Fc Tag.
- Purpose
- CD272 [BTLA] (human):Fc (mouse) (rec.)
- Specificity
- The extracellular domain of human CD272 (aa 31-157) is fused to the N-terminus of the Fc region of mouse IgG2a.
- Characteristics
- Protein. The extracellular domain of human CD272 (aa 31-157) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). BTLA is a type I transmembrane glycoprotein of the CD28 family of T cell costimulatory molecules. BTLA functions as a coinhibitor on activated T cells and on B cells and dendritic cells. The extracellular domain (ECD) of this Ig superfamily protein contains one V-type Ig-like domain, which interacts with HVEM.
- Purity
- >98 % (SDS-PAGE)
- Endotoxin Level
- <0.06EU/μg protein (LAL test, Lonza).
- Biological Activity Comment
- Measured in a competitive binding assay.
- Top Product
- Discover our top product BTLA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized from 0.2μm-filtered solution in PBS.
- Handling Advice
- Avoid freeze/thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- Target
- BTLA (B and T Lymphocyte Associated (BTLA))
- Alternative Name
- CD272 [BTLA] (BTLA Products)
- Synonyms
- BTLA Protein, BTLA1 Protein, CD272 Protein, A630002H24 Protein, B and T lymphocyte associated Protein, BTLA Protein, Btla Protein
- Background
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Alternate Names/Synonyms: BTLA, B- and T-lymphocyte attenuator
Product Description: BTLA is a type I transmembrane glycoprotein of the CD28 family of T cell costimulatory molecules. BTLA functions as a coinhibitor on activated T cells and on B cells and dendritic cells. The extracellular domain (ECD) of this Ig superfamily protein contains one V-type Ig-like domain, which interacts with HVEM.
- NCBI Accession
- NP_861445
- Pathways
- Cancer Immune Checkpoints
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