M-CSF/CSF1 Protein (AA 33-190) (His tag)
-
- Target See all M-CSF/CSF1 (CSF1) Proteins
- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 33-190
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This M-CSF/CSF1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- MCSF, 33-190 aa, Human, His-tagged, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CSF1 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0), 2mM DTT, 10% glycerol
- Storage
- 4 °C
-
- Target
- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
- Alternative Name
- MCSF (CSF1 Products)
- Synonyms
- CSF-1 Protein, MCSF Protein, C87615 Protein, Csfm Protein, op Protein, csf1-1 Protein, zgc:172186 Protein, CSF1 Protein, csf1-2 Protein, zgc:158436 Protein, colony stimulating factor 1 Protein, colony stimulating factor 1 (macrophage) Protein, colony stimulating factor 1a (macrophage) Protein, macrophage colony-stimulating factor 1 Protein, macrophage colony stimulating factor Protein, colony stimulating factor 1b (macrophage) Protein, CSF1 Protein, Csf1 Protein, csf1a Protein, LOC396599 Protein, LOC100860895 Protein, csf1b Protein
- Background
- Macrophage colony stimulating factor (M-CSF), as known as CSF-1, one of the hematopoietic growth factors that regulate the growth and differentiation of blood cells. This protein is produced by monocytes, granulocytes, endothelial cells, and fibroblasts. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osteoclasts. Recombinant human M-CSF, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. . Synonyms: CSF1 , Macrophage colony stimulating factor Colony stimulating factor 1, CSF 1, Lanimostim, M CSF, Macrophage Colony Stimulating Factor 1, MCSF, MGC31930. NCBI no.: NP_757351
- Molecular Weight
- 20.7 kDa (179aa), confirmed by MALDI-TOF.
- Pathways
- RTK Signaling
-