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IL-6 Protein (AA 30-212) (His tag)

IL6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666780
  • Target See all IL-6 (IL6) Proteins
    IL-6 (IL6) (Interleukin 6 (IL6))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 30-212
    Origin
    • 30
    • 15
    • 12
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 47
    • 24
    • 20
    • 5
    • 4
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IL-6 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    Interleukin 6, 30-212 aa, Human, His-tagged, Recombinant, E.coli
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product IL6 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In Phosphate Buffered Saline (pH7.4) containing 10% glycerol
    Storage
    4 °C
  • Target
    IL-6 (IL6) (Interleukin 6 (IL6))
    Alternative Name
    Interleukin 6 (IL6 Products)
    Synonyms
    BSF2 Protein, HGF Protein, HSF Protein, IFNB2 Protein, IL-6 Protein, Il-6 Protein, ILg6 Protein, Ifnb2 Protein, il6 Protein, CHIL-6 Protein, interleukin 6 Protein, interleukin-6 Protein, IL6 Protein, Il6 Protein, il-6 Protein, IL-6 Protein
    Background
    Interleukin-6, as known as IL-6, is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is also a 'myokine,' a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 acts as both a pro-inflammatory and anti-inflammatory cytokine. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6. It is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10. Recombinant interleukin-6 was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: HGF, HSF, BSF2, IL-6, IFNB2, IL6, interleukin 6 (interferon, beta 2),. NCBI no.: NP_000591
    Molecular Weight
    23.1 kDa (204 aa), confirmed by MALDI-TOF.
    Pathways
    TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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