AKR1C4 Protein (AA 1-323) (His tag)
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- Target See all AKR1C4 Proteins
- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-323
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AKR1C4 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- AKR1C4, 1-323aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product AKR1C4 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
- Storage
- 4 °C
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- Target
- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
- Alternative Name
- AKR1C4 (AKR1C4 Products)
- Synonyms
- 3-alpha-HSD Protein, C11 Protein, CDR Protein, CHDR Protein, DD-4 Protein, DD4 Protein, HAKRA Protein, aldo-keto reductase family 1 member C4 Protein, AKR1C4 Protein
- Background
- AKR1C4 belongs to aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. It catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. Recombinant human AKR1C4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Aldo-keto reductase family 1 member C4, DHEA-ST, DHEAS, HST, hSTa, ST2, ST2A1, ST2A3. NCBI no.: NP_001809
- Molecular Weight
- 39.2 kDa(343aa), confirmed by MALDI-TOF
- Pathways
- Steroid Hormone Biosynthesis
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