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L1CAM Protein (His tag)

L1CAM Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN6964088
  • Target See all L1CAM Proteins
    L1CAM (L1 Cell Adhesion Molecule (L1CAM))
    Protein Type
    Recombinant
    Origin
    • 10
    • 6
    • 2
    Human
    Source
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This L1CAM protein is labelled with His tag.
    Purpose
    Recombinant Human CD171 Protein with C-terminal 6xHis tag
    Specificity
    CD171 (Ile20-Glu1120) 6xHis tag
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product L1CAM Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Preservative
    Without preservative
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    L1CAM (L1 Cell Adhesion Molecule (L1CAM))
    Alternative Name
    CD171 (L1CAM Products)
    Synonyms
    l1cam-a Protein, CAML1 Protein, CD171 Protein, HSAS Protein, HSAS1 Protein, MASA Protein, MIC5 Protein, N-CAM-L1 Protein, N-CAML1 Protein, NCAM-L1 Protein, S10 Protein, SPG1 Protein, L1 Protein, Hsas Protein, Hyd Protein, NCAML1 Protein, L1 cell adhesion molecule S homeolog Protein, L1 cell adhesion molecule Protein, l1cam.S Protein, L1CAM Protein, L1cam Protein
    Background
    Synonymes: CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1
    Description: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
    Molecular Weight
    predicted molecular mass of 124.0 kDa after removal of the signal peptide.The apparent molecular mass of CD171-His is 130-250 kDa due to glycosylation.
    Gene ID
    3897
    UniProt
    P32004
    Pathways
    Synaptic Membrane
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