MERTK Protein (Fc Tag)
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- Target See all MERTK Proteins
- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MERTK protein is labelled with Fc Tag.
- Purpose
- Recombinant human MERTK protein with C-terminal human Fc tag
- Specificity
- MERTK (Ala21-Ile505) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- affinity purification
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product MERTK Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
- Alternative Name
- MERTK (MERTK Products)
- Synonyms
- MER Protein, RP38 Protein, c-mer Protein, Eyk Protein, Mer Protein, Nyk Protein, nmf12 Protein, rdy Protein, C-EYK Protein, MERTK Protein, DKFZp469D2215 Protein, si:ch1073-268l12.2 Protein, MER proto-oncogene, tyrosine kinase Protein, c-mer proto-oncogene tyrosine kinase Protein, c-mer proto-oncogene tyrosine kinase a Protein, MERTK Protein, Mertk Protein, mertka Protein
- Background
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Synonymes: c-Eyk, c-mer, MER, RP38, Tyro12
Description: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008] - Molecular Weight
- predicted molecular mass of 78.8 kDa after removal of the signal peptide. The apparent molecular mass of MERTK-hFc is 100-130 kDa due to glycosylation.
- UniProt
- Q12866
- Pathways
- RTK Signaling
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