GUCY2C Protein (AA 24-430) (Fc Tag)
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- Target See all GUCY2C Proteins
- GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-430
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GUCY2C protein is labelled with Fc Tag.
- Purpose
- Human GUCY2C/Guanylyl cyclase C Protein
- Sequence
- Ser24-Gln430
- Characteristics
- Recombinant Human GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser24-Gln430.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human GUCY2C, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-GUCY2C Antibody, hFc Tag with the EC50 of 15.0ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product GUCY2C Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))
- Alternative Name
- GUCY2C (GUCY2C Products)
- Synonyms
- DIAR6 Protein, GUC2C Protein, MECIL Protein, MUCIL Protein, STAR Protein, AI893437 Protein, GC-C Protein, Gcc Protein, GCC Protein, gucy2c-A Protein, GUCY2C Protein, Gucy2c Protein, guanylate cyclase 2C Protein, guanylate cyclase 2c Protein, guanylate cyclase 2C L homeolog Protein, GUCY2C Protein, Gucy2c Protein, gucy2c.L Protein, gucy2c Protein
- Background
- Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
- Molecular Weight
- 72.8 kDa. Due to glycosylation, the protein migrates to 85-115 kDa based on Tris-Bis PAGE result.
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