Glucagon Receptor Protein (GCGR) (Fc Tag)
GCGR
Origin: Mouse
Host: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
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- Target See all Glucagon Receptor (GCGR) Proteins
- Glucagon Receptor (GCGR)
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Glucagon Receptor protein is labelled with Fc Tag.
- Purpose
- Mouse GCGR / Glucagon receptor Protein, Fc Tag
- Sequence
- Ala 27 - Lys 137
- Characteristics
- Mouse GCGR, Fc Tag (GCR-M5254) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Lys 137 (Accession # Q61606-1).
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GCGR Protein
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Glucagon Receptor (GCGR) (AA 26-136) protein (His tag)
GCGR Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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- Application Notes
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 39.5 kDa. The protein migrates as 50-65 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- Glucagon Receptor (GCGR)
- Alternative Name
- GCGR / Glucagon receptor (GCGR Products)
- Synonyms
- GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein
- Background
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Synonyms: Glucagon R, GCGR,Glucagon receptor,
Description: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system. - Molecular Weight
- 39.5 kDa
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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