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GAS6 Protein (AA 279-678) (His tag)

MALS verified GAS6 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7121477
  • Target See all GAS6 Proteins
    GAS6 (Growth Arrest-Specific 6 (GAS6))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 279-678
    Origin
    • 9
    • 4
    • 4
    • 1
    Human
    Source
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This GAS6 protein is labelled with His tag.
    Purpose
    Human GAS6 (279-678) Protein, His Tag (MALS verified)
    Sequence
    Asp 279 - Ala 678
    Characteristics
    Human GAS6, His Tag (GA6-H5249) is expressed from human 293 cells (HEK293). It contains AA Asp 279 - Ala 678 (Accession # Q14393-2).
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Grade
    MALS verified
    Top Product
    Discover our top product GAS6 Protein
  • Application Notes
    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 46.0 kDa. The protein migrates as 45-50 kDa under reducing (R) condition due to glycosylation.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    GAS6 (Growth Arrest-Specific 6 (GAS6))
    Alternative Name
    GAS6 (GAS6 Products)
    Synonyms
    fj34a12 Protein, zgc:63860 Protein, wu:fj34a12 Protein, MGC68463 Protein, gas6 Protein, MGC83872 Protein, GAS6 Protein, Gas-6 Protein, AXLLG Protein, AXSF Protein, growth arrest specific 6 Protein, growth arrest-specific 6 Protein, growth arrest specific 6 L homeolog Protein, growth arrest specific 6 S homeolog Protein, GAS6 Protein, gas6 Protein, gas6.L Protein, gas6.S Protein, Gas6 Protein
    Background
    Synonyms: GAS6,GAS-6,AXLLG,
    Description: GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
    Molecular Weight
    46.0 kDa
    NCBI Accession
    NP_000811
    Pathways
    RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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