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CD25 Protein (Fc Tag)

IL2RA Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7318603
  • Target See all CD25 (IL2RA) Proteins
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 19
    • 11
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 15
    • 9
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CD25 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human IL2Ra/CD25 Protein (Fc Tag)(Active)
    Sequence
    Glu22-Cys213
    Characteristics
    Recombinant Human Interleukin-2 Receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu22-Cys213 is expressed with a Fc tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized Human IL-2RA-Fc at 10μg/ml(100 μl/well) can bind Human IL-2-His(Cat: PKSH032629). The ED50 of Human IL-2RA-Fc is 0.46 ug/mL
    Top Product
    Discover our top product IL2RA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Alternative Name
    IL2Ra/CD25 (IL2RA Products)
    Synonyms
    CD25 Protein, IDDM10 Protein, IL2R Protein, TCGFR Protein, IL2RAC Protein, IL-2RA Protein, Il2r Protein, Ly-43 Protein, interleukin 2 receptor subunit alpha Protein, interleukin-2 receptor subunit alpha-like Protein, interleukin 2 receptor, alpha chain Protein, IL2RA Protein, Il2ra Protein, LOC100222957 Protein
    Background

    Background: Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane protein, contains 2 Sushi (CCP/SCR) domains. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.

    Synonym: Interleukin-2 receptor subunit alpha,CD25,p55,TAC antigen,IL2-RA,IL-2R subunit alpha,IL-2-RA,IL-2 receptor subunit alpha, IL-2Rα,IDDM10,IL2R,p55,TCGFR

    Molecular Weight
    48.9 kDa
    UniProt
    P01589
    Pathways
    JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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