CD25 Protein (Fc Tag)
Quick Overview for CD25 Protein (Fc Tag) (ABIN7318603)
Target
See all CD25 (IL2RA) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purification tag / Conjugate
- This CD25 protein is labelled with Fc Tag.
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Purpose
- Recombinant Human IL2Ra/CD25 Protein (Fc Tag)(Active)
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Sequence
- Glu22-Cys213
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Characteristics
- Recombinant Human Interleukin-2 Receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu22-Cys213 is expressed with a Fc tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Immobilized Human IL-2RA-Fc at 10μg/ml(100 μl/well) can bind Human IL-2-His(Cat: PKSH032629). The ED50 of Human IL-2RA-Fc is 0.46 ug/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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Alternative Name
- IL2Ra/CD25
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Background
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Background: Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane protein, contains 2 Sushi (CCP/SCR) domains. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.
Synonym: Interleukin-2 receptor subunit alpha,CD25,p55,TAC antigen,IL2-RA,IL-2R subunit alpha,IL-2-RA,IL-2 receptor subunit alpha, IL-2Rα,IDDM10,IL2R,p55,TCGFR
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Molecular Weight
- 48.9 kDa
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UniProt
- P01589
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Pathways
- JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
Target
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