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CD25 Protein (Fc Tag)

This Recombinant CD25 protein is produced in Human Cells.
Catalog No. ABIN7318603
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Quick Overview for CD25 Protein (Fc Tag) (ABIN7318603)

Target

See all CD25 (IL2RA) Proteins
CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 19
  • 11
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 13
  • 10
  • 8
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This CD25 protein is labelled with Fc Tag.

    Purpose

    Recombinant Human IL2Ra/CD25 Protein (Fc Tag)(Active)

    Sequence

    Glu22-Cys213

    Characteristics

    Recombinant Human Interleukin-2 Receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu22-Cys213 is expressed with a Fc tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Immobilized Human IL-2RA-Fc at 10μg/ml(100 μl/well) can bind Human IL-2-His(Cat: PKSH032629). The ED50 of Human IL-2RA-Fc is 0.46 ug/mL
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

    Alternative Name

    IL2Ra/CD25

    Background

    Background: Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane protein, contains 2 Sushi (CCP/SCR) domains. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.

    Synonym: Interleukin-2 receptor subunit alpha,CD25,p55,TAC antigen,IL2-RA,IL-2R subunit alpha,IL-2-RA,IL-2 receptor subunit alpha, IL-2Rα,IDDM10,IL2R,p55,TCGFR

    Molecular Weight

    48.9 kDa

    UniProt

    P01589

    Pathways

    JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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