CD25 Protein (Fc Tag)
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- Target See all CD25 (IL2RA) Proteins
- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD25 protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse IL-2-RA/CD25 Protein
- Sequence
- ELCLYDPPEV PNATFKALSY KNGTILNCEC KRGFRRLKEL VYMRCLGNSW SSNCQCTSNS HDKSRKQVTA QLEHQKEQQT TTDMQKPTQS MHQENLTGHC REPPPWKHED SKRIYHFVEG QSVHYECIPG YKALQRGPAI SICKMKCGKT GWTQPQLTCV DEREHHRFLA SEESQGSRNS SPESETSCPI TTTDFPQPTE TTAMTETFVL TMEYK
- Specificity
- Glu22-Lys236
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <0.1EU/μg
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA.Immobilized APC anti-mouse CD25 Antibody at 1μg/mL (100 μL/well) can bind Mouse CD25 with a linear range of 0.46-6 ng/mL.
- Top Product
- Discover our top product IL2RA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
- Alternative Name
- IL-2-RA/CD25 (IL2RA Products)
- Synonyms
- CD25 Protein, IDDM10 Protein, IL2R Protein, TCGFR Protein, IL2RAC Protein, IL-2RA Protein, Il2r Protein, Ly-43 Protein, interleukin 2 receptor subunit alpha Protein, interleukin-2 receptor subunit alpha-like Protein, interleukin 2 receptor, alpha chain Protein, IL2RA Protein, Il2ra Protein, LOC100222957 Protein
- Background
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Description: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown.
Name: CD25, Il2r, Ly-43, p55, CD25, IL2R, IMD41, TCGFR, IDDM10
- Gene ID
- 16184
- UniProt
- P01590
- Pathways
- JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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