RAB7A Protein (His tag)
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- Target See all RAB7A Proteins
- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
- Protein Type
- Recombinant
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RAB7A protein is labelled with His tag.
- Purpose
- Recombinant Rat RAB7A/Rab-7a Protein (His Tag)
- Sequence
- Met1-Cys207
- Characteristics
- A DNA sequence encoding the rat Rab7a (NP_076440.1) (Met1-Cys207) was expressed with a polyhistidine tag at the N-terminus.
- Purity
- > 90 % as determined by SDS-PAGE
- Top Product
- Discover our top product RAB7A Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
- Alternative Name
- RAB7A/Rab-7a (RAB7A Products)
- Synonyms
- RAB5 Protein, PRO2706 Protein, RAB7 Protein, Rab7 Protein, rab7 Protein, pro2706 Protein, RAB7A Protein, LOC100231734 Protein, ARABIDOPSIS RAB GTPASE HOMOLOG G2 Protein, ATRAB7A Protein, ATRABG2 Protein, F7D8.20 Protein, F7D8_20 Protein, RAB GTPase homolog 7A Protein, DDBDRAFT_0190210 Protein, DDBDRAFT_0191507 Protein, DDB_0190210 Protein, DDB_0191507 Protein, Rab7a Protein, rab-7 Protein, zgc:64058 Protein, RAB5A, member RAS oncogene family Protein, RAB7A, member RAS oncogene family Protein, RAB7A, member RAS oncogene family L homeolog Protein, rab7A protein Protein, RAB GTPase homolog 7A Protein, Rab GTPase Protein, ras-related protein rab-7a Protein, RAB7, member RAS oncogene family Protein, RAB5A Protein, RAB7A Protein, Rab7a Protein, rab7a.L Protein, rab7a Protein, rab7A Protein, Rab7 Protein, rab7 Protein
- Background
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Background: RAB7A is a ubiquitous small GTPase, which controls transport to late endocytic compartments. Silencing or overexpression of wild type RAB7A changed the soluble/insoluble rate of peripherin indicating that RAB7A is important for peripherin organization and function. In addition, disease-causing RAB7A mutant proteins bind more strongly to peripherin and their expression causes a significant increase in the amount of soluble peripherin. The altered interaction between disease-causing RAB7A mutants and peripherin could play an important role in CMT2B neuropathy.
Synonym: Rab7
- Molecular Weight
- 25.7 kDa
- NCBI Accession
- NP_076440
- Pathways
- EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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