SARS-CoV Spike Protein (R667A, Trimer) (His tag)

Catalog No. ABIN7271647

Product Details

Target: SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))

Protein Type: Recombinant

Protein Characteristics: R667A, Trimer

Origin: SARS Coronavirus GD01

Source: HEK-293 Cells

Purification tag / Conjugate: This SARS-CoV Spike protein is labelled with His tag.

Purpose: SARS-CoV GD01 Spike Trimer (R667A, KV968-969PP), His Tag (MALS verified)

Sequence: Ser 14 - Pro 1195

Characteristics: SARS-CoV GD01 Spike Trimer, His Tag (SPN-S52Ht) is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Pro 1195 (Accession # AAP51227.1 (R667A, KV968-969PP).

Purity: >90 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Grade: MALS verified

Application Details

Application Notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 136.5 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))

Alternative Name: SARS-CoV Spike (SARS-CoV S Products)

Background: Synonyms:Spike,S protein,Spike glycoprotein,S glycoprotein,Description:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Molecular Weight: 136.5 kDa