SARS-CoV Spike Protein (K669A) (His tag)

Catalog No. ABIN7273436

Product Details

Target: SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))

Protein Type: Recombinant

Protein Characteristics: K669A

Origin: Kenya Bat Coronavirus

Source: HEK-293 Cells

Purification tag / Conjugate: This SARS-CoV Spike protein is labelled with His tag.

Purpose: SARS-CoV BtKY72 Spike Trimer (K669A, KV971-972PP), His Tag

Sequence: Thr 13 - Pro 1198

Characteristics: SARS-CoV BtKY72 Spike Trimer, His Tag (SPN-S52Hu) is expressed from human 293 cells (HEK293). It contains AA Thr 13 - Pro 1198 (Accession # A0A3Q8AKM0 (K669A, KV971-972PP).

Purity: >95 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Application Notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 136.7 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: SARS-CoV Spike (SARS-CoV S) (SARS-Coronavirus Spike Protein (SARS-CoV S))

Alternative Name: SARS-CoV Spike (SARS-CoV S Products)

Background: Synonyms:Spike,S protein,Spike glycoprotein,S glycoprotein,Description:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Molecular Weight: 136.7 kDa