Betacellulin Protein (BTC) (Fc Tag)
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- Target See all Betacellulin (BTC) Proteins
- Betacellulin (BTC)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Betacellulin protein is labelled with Fc Tag.
- Purpose
- Recombinant Human Betacellulin/BTC Protein
- Sequence
- DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY
- Specificity
- Asp32-Tyr111
- Purity
- > 92 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <0.1EU/μg
- Top Product
- Discover our top product BTC Protein
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Betacellulin (BTC) (AA 32-111) protein (His tag)
BTC Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Betacellulin (BTC) (AA 1-178) protein (GST tag)BTC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Betacellulin (BTC) (AA 70-178) protein (GST tag)BTC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Betacellulin (BTC) (AA 32-118) protein (His tag)BTC Origin: Human Host: Yeast Recombinant > 90 % ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Concentration
- 0.8 mg/mL
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- Betacellulin (BTC)
- Alternative Name
- Betacellulin/BTC (BTC Products)
- Synonyms
- BTC Protein, LOC100228121 Protein, probetacellulin Protein, Bcn Protein, betacellulin Protein, betacellulin, epidermal growth factor family member Protein, BTC Protein, LOC100228121 Protein, Btc Protein
- Background
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Description: Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth factor receptor (EGFR), neu/ErbB-2/HER2, ErbB-3/HER3 and ErbB-4/HER4). Betacellulin is a 32-kilodalton glycoprotein that appears to be processed from a larger transmembrane precursor by proteolytic cleavage. This protein is a ligand for the EGF receptor. BTC is a polymer of about 62-111 amino acid residues. Secondary Structure: 6 % helical (1 helices, 3 residues)36 % beta sheet (5 strands, 18 residues). BTC was originally identified as a growth-promoting factor in mouse pancreatic β-cell carcinoma cell line and has since been identified in humans. It plays a role in the growth and development of the neonate and/or mammary gland function. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Name: BTC,Betacellulin
- Gene ID
- 685
- UniProt
- P35070
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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