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IL1RL1 Protein (Fc Tag)

IL1RL1 Origin: Mouse Host: HEK-293 Cells Recombinant > 92 % by SDS-PAGE.
Catalog No. ABIN7536248
  • Target See all IL1RL1 Proteins
    IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
    Protein Type
    Recombinant
    Origin
    • 18
    • 10
    Mouse
    Source
    • 13
    • 5
    • 4
    • 4
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This IL1RL1 protein is labelled with Fc Tag.
    Purpose
    Recombinant Mouse IL1RL1 Protein
    Sequence
    SKSSWGLENE ALIVRCPQRG RSTYPVEWYY SDTNESIPTQ KRNRIFVSRD RLKFLPARVE DSGIYACVIR SPNLNKTGYL NVTIHKKPPS CNIPDYLMYS TVRGSDKNFK ITCPTIDLYN WTAPVQWFKN CKALQEPRFR AHRSYLFIDN VTHDDEGDYT CQFTHAENGT NYIVTATRSF TVEEKGFSMF PVITNPPYNH TMEVEIGKPA SIACSACFGK GSHFLADVLW QINKTVVGNF GEARIQEEEG RNESSSNDMD CLTSVLRITG VTEKDLSLEY DCLALNLHGM IRHTIRLRRK QPIDHR
    Specificity
    Ser27-Arg332
    Purity
    > 92 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    <0.1EU/μg
    Top Product
    Discover our top product IL1RL1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
    Alternative Name
    IL1RL1 (IL1RL1 Products)
    Synonyms
    DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, FIT-1 Protein, IL33R Protein, ST2 Protein, ST2V Protein, FIT1 Protein, interleukin 1 receptor-like 1 Protein, interleukin 1 receptor like 1 Protein, Il1rl1 Protein, IL1RL1 Protein
    Background

    Description: IL-1 receptor-like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.

    Name: T1, St2, DER4, Ly84, ST2L, Fit-1, T1/ST2, St2-rs1,IL1RL1

    Gene ID
    17082
    UniProt
    P14719
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