anti-Gibbon Metabotropic Glutamate Receptor 5 antibody for Immunohistochemistry

Recommended Metabotropic Glutamate Receptor 5 Antibody (supplied by: Log in to see )

Antigen
Glutamate Receptor, Metabotropic 5 (GRM5) Antibodies
  • GPRC1E
  • MGLUR5
  • mGlu5
  • mGluR5
  • mGlur5
  • 6430542K11Rik
  • AI850523
  • Glu5R
  • Gprc1e
  • mGluR5b
  • glutamate receptor, metabotropic 5
  • glutamate metabotropic receptor 5
  • GRM5
  • Grm5
Epitope
N-Term
70
61
15
13
12
7
4
3
3
3
2
2
2
1
Reactivity
Bat, Chicken, Cow (Bovine), Dog (Canine), Gibbon, Hamster, Horse (Equine), Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
185
131
120
6
6
4
4
2
2
2
1
1
Host
Rabbit
97
89
4
2
Clonality
Polyclonal
Conjugate
This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
7
7
7
6
6
6
4
4
4
4
4
4
4
4
4
4
4
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
159
103
71
57
48
38
37
22
13
12
4
3
2
1
1
Options
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Available images

Catalog No. ABIN2469508
$ 618.75
Plus shipping costs $45.00

General

Antigen Glutamate Receptor, Metabotropic 5 (GRM5) Antibodies
Epitope N-Term
(70), (61), (15), (13), (12), (7), (4), (3), (3), (3), (2), (2), (2), (1)
Reactivity Bat, Chicken, Cow (Bovine), Dog (Canine), Gibbon, Hamster, Horse (Equine), Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(185), (131), (120), (6), (6), (4), (4), (2), (2), (2), (1), (1)
Host Rabbit
(97), (89), (4), (2)
Clonality
Polyclonal
Conjugate This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
(7), (7), (7), (6), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC)
(159), (103), (71), (57), (48), (38), (37), (22), (13), (12), (4), (3), (2), (1), (1)
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Product Details anti-Metabotropic Glutamate Receptor 5 Antibody

Target Details Metabotropic Glutamate Receptor 5 Application Details Handling Images
Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purification Immunoaffinity Chromatography
Immunogen GRM5 antibody was raised against a peptide located in the N-Terminal extracellular domain of GRM5 (Human).
Plasmids, Primers & others

Target Details Metabotropic Glutamate Receptor 5

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name GRM5 (GRM5 Antibody Abstract)
Background Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternative splice variants of GRM5 have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. GRM5 is involved in inflammatory mechanical hyperalgesia and potentially in schizophrenia
Gene ID 2915
UniProt P41594
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody Target Details Metabotropic Glutamate Receptor 5 Handling Images back to top
Application Notes GRM5 antibody can be used in Western Blot starting at 1:100, and immunohistochemistry starting at 1:100.
Restrictions For Research Use only

Handling

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody Target Details Metabotropic Glutamate Receptor 5 Application Details Images back to top
Format Liquid
Buffer PBS, 0.1 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice As with all antibodies avoid freeze/thaw cycles.
Storage 4 °C/-80 °C
Storage Comment GRM5 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Images

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody Target Details Metabotropic Glutamate Receptor 5 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Glutamate Receptor, Metabotropic 5 (GRM5) (N-Term) antibody (ABIN2469508) anti-Glutamate Receptor, Metabotropic 5 (GRM5) (N-Term) antibody