anti-Mouse (Murine) Metabotropic Glutamate Receptor 5 antibody for Enzyme Immunoassay

Recommended Metabotropic Glutamate Receptor 5 Antibody

Antigen
Glutamate Receptor, Metabotropic 5 (GRM5) Antibodies
  • GPRC1E
  • MGLUR5
  • mGlu5
  • mGluR5
  • mGlur5
  • 6430542K11Rik
  • AI850523
  • Glu5R
  • Gprc1e
  • mGluR5b
  • glutamate receptor, metabotropic 5
  • glutamate metabotropic receptor 5
  • GRM5
  • Grm5
Reactivity
Human, Mouse (Murine), Rat (Rattus)
208
164
154
7
7
5
5
3
3
3
2
2
1
Host
Rabbit
118
91
4
2
Clonality
Polyclonal
Conjugate
This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
12
10
7
6
6
6
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
174
113
83
68
58
37
36
21
13
4
4
2
2
1
Options

Available images

Catalog No. ABIN317705
$ 434.50
Plus shipping costs $45.00

General

Antigen Glutamate Receptor, Metabotropic 5 (GRM5) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(208), (164), (154), (7), (7), (5), (5), (3), (3), (3), (2), (2), (1)
Host Rabbit
(118), (91), (4), (2)
Clonality
Polyclonal
Conjugate This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
(12), (10), (7), (6), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(174), (113), (83), (68), (58), (37), (36), (21), (13), (4), (4), (2), (2), (1)
Supplier

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody

Target Details Metabotropic Glutamate Receptor 5 Application Details Handling Images
Specificity This antibody detects endogenous levels of mGluR5 / GRM5 protein (region surrounding Lys56).
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity-chromatography
Plasmids, Primers & others

Target Details Metabotropic Glutamate Receptor 5

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name mGluR5 / GRM5 (GRM5 Antibody Abstract)
Background The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.Synonyms: GPRC1E, MGLUR5, Metabotropic glutamate receptor 5
Molecular Weight approx. 132 kDa
Gene ID 2915
NCBI Accession NP_000833
UniProt P41594
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody Target Details Metabotropic Glutamate Receptor 5 Handling Images back to top
Application Notes ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody Target Details Metabotropic Glutamate Receptor 5 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody Target Details Metabotropic Glutamate Receptor 5 Application Details Handling back to top
Supplier Images
 image for anti-Glutamate Receptor, Metabotropic 5 (GRM5) antibody (ABIN317705) anti-Glutamate Receptor, Metabotropic 5 (GRM5) antibody