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|Antigen||serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1) Antibodies|
|Reactivity||Rat (Rattus), Mouse (Murine), Human Alternatives|
Western Blotting (WB)
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|Specificity||Rabbit Anti-Neuroserpin Polyclonal Antibody detects endogenous levels of mouse and rat Neuroserpin. It is predicted to react with human Neuroserpin according to sequence homology.Positive control:mouse brain and rat brain.|
|Cross-Reactivity (Details)||Rabbit Anti-Neuroserpin Polyclonal Antibody detects endogenous levels of mouse and rat Neuroserpin. It is predicted to react with human Neuroserpin according to sequence homology. Positive control:mouse brain and rat brain.|
|Immunogen||KLH-coupled synthetic peptide from C-terminal of human Neuroserpin .|
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|Alternative Name||Neuroserpin (SERPINI1 Antibody Abstract)|
Neuroserpin is a member of the serpin superfamily. It is secreted from axonal growth cones of the CNS and PNS where it inhibits the enzyme tissue plasminogen activator. Neuroserpin participates in regulating axonal growth, reducing seizure activity, controlling damage in cerebral infarction, and regulating emotional behavior and memory. This protein is expressed in brain.
Rabbit Anti-Neuroserpin Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Neuroserpin (Swiss Prot: Q99574).
|Pathways||Regulation of Hormone Metabolic Process|
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Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 1-2 µg/mLOther Applications: user -optimized
|Restrictions||For Research Use only|
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|Buffer||PBS, pH 7.4, containing 0.02 % sodium azide|
|Precaution of Use||WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.|
|Storage||4 °C/-20 °C|
|Storage Comment||The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.|
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