anti-Human Phospholipase C gamma 2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Phospholipase C gamma 2 Antibody (supplied by: Log in to see )

Antigen
Phospholipase C gamma 2 (PLCG2) Antibodies
  • PLCgamma2
  • Plcg-2
  • APLAID
  • FCAS3
  • phospholipase C, gamma 2
  • phospholipase C gamma 2
  • phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • Plcg2
  • PLCG2
Epitope
Tyr1217
50
49
42
18
15
6
5
5
5
4
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
292
178
167
12
4
4
4
4
3
1
Host
Rabbit
240
52
Clonality
Polyclonal
Conjugate
This Phospholipase C gamma 2 antibody is un-conjugated
6
6
5
5
5
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
213
115
63
59
43
40
36
16
14
10
3
3
2
1
Options
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Catalog No. ABIN6653035
$ 415.84
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
7 ABIN1804116 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
7 ABIN2888692 ELISA IHC IHC (p) WB Rabbit IgG AA 1186-1235 Log in to see Polyclonal 0
7 ABIN271905 EIA IHC (p) WB Rabbit Log in to see Polyclonal 0
7 ABIN5585795 ELISA IHC (p) WB Rabbit Log in to see Polyclonal 0
7 ABIN5585794 ELISA IHC (p) WB Rabbit Log in to see Polyclonal 0
7 ABIN5585797 IF IHC (p) Rabbit Log in to see Polyclonal 0
6.8131986 ABIN4346133 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
5.5 ABIN700375 IF (p) IHC (p) WB Rabbit IgG AA 660-710 Log in to see Polyclonal 1
5.5 ABIN744848 IF (p) IHC (p) WB Rabbit IgG pTyr759 Log in to see Polyclonal 1
4 ABIN2878867 ELISA IHC IHC (p) WB Rabbit IgG AA 721-770 Log in to see Polyclonal 0
4 ABIN6652931 IHC (p) Rabbit pTyr1217 Log in to see Polyclonal 3
4 ABIN5956495 ELISA IHC (p) WB Rabbit IgG pTyr753 Log in to see Polyclonal 0
4 ABIN5956494 ELISA IHC (p) WB Rabbit IgG Tyr685, Tyr753 Log in to see Polyclonal 0
4 ABIN1738145 IHC (p) ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 0
4 ABIN272070 IHC (p) WB Rabbit Log in to see Polyclonal 0
4 ABIN4948338 IHC (p) Rabbit pTyr1217 Log in to see Polyclonal 0
3.8131986 ABIN443064 ICC IF IHC (p) IHC WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN700384 IHC (p) WB HRP Rabbit IgG AA 660-710 Log in to see Polyclonal 0
1 ABIN700377 IHC (p) WB Biotin Rabbit IgG AA 660-710 Log in to see Polyclonal 0
1 ABIN2884254 ELISA IF IHC IHC (p) WB Rabbit IgG pTyr1217 Log in to see Polyclonal 0

General

Antigen Phospholipase C gamma 2 (PLCG2) Antibodies
Epitope Tyr1217
(50), (49), (42), (18), (15), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(292), (178), (167), (12), (4), (4), (4), (4), (3), (1)
Host Rabbit
(240), (52)
Clonality
Polyclonal
Conjugate This Phospholipase C gamma 2 antibody is un-conjugated
(6), (6), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(213), (115), (63), (59), (43), (40), (36), (16), (14), (10), (3), (3), (2), (1)
Pubmed 4 references available
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Product Details anti-Phospholipase C gamma 2 Antibody

Target Details Phospholipase C gamma 2 Application Details Handling References for anti-Phospholipase C gamma 2 antibody (ABIN6653035) Images
Specificity This antibody detects endogenous levels of total PLC-gamma 2 protein.
Purification Immunoaffinity Chromatography
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human PLC-gamma 2 around the phosphorylation site of Tyrosine 1217 (F-L-YP-D-T).
Plasmids, Primers & others

Target Details Phospholipase C gamma 2

Product Details anti-Phospholipase C gamma 2 Antibody Application Details Handling References for anti-Phospholipase C gamma 2 antibody (ABIN6653035) Images back to top
Antigen
Alternative Name PLCG2 (PLCG2 Antibody Abstract)
Background Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2, PLC-IV, PLC-gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2
Gene ID 5336
NCBI Accession NP_002652
UniProt P16885
Pathways RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling

Application Details

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Handling References for anti-Phospholipase C gamma 2 antibody (ABIN6653035) Images back to top
Application Notes Immunohistochemistry (1/50-1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details References for anti-Phospholipase C gamma 2 antibody (ABIN6653035) Images back to top
Concentration 1,0 mg/mL
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at-20 °C.

References for anti-Phospholipase C gamma 2 antibody (ABIN6653035)

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details Handling Images back to top
Background publications

Watanabe, Hashimoto, Ishiai, Matsushita, Baba, Kishimoto, Kurosaki, Tsukada: "Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling." in: The Journal of biological chemistry, Vol. 276, Issue 42, pp. 38595-601, 2001

Yue, Ku, Liu, Simon, Sanborn: "Molecular mechanism of the inhibition of phospholipase C beta 3 by protein kinase C." in: The Journal of biological chemistry, Vol. 275, Issue 39, pp. 30220-5, 2000

Singer, Brown, Sternweis: "Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D." in: Annual review of biochemistry, Vol. 66, pp. 475-509, 1997

Smrcka, Hepler, Brown, Sternweis: "Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq." in: Science (New York, N.Y.), Vol. 251, Issue 4995, pp. 804-7, 1991

Images

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details Handling References for anti-Phospholipase C gamma 2 antibody (ABIN6653035) back to top
Supplier Images
 image for anti-Phospholipase C gamma 2 (PLCG2) (Tyr1217) antibody (ABIN6653035) anti-Phospholipase C gamma 2 (PLCG2) (Tyr1217) antibody
 image for anti-Phospholipase C gamma 2 (PLCG2) (Tyr1217) antibody (ABIN6653035) anti-Phospholipase C gamma 2 (PLCG2) (Tyr1217) antibody (Image 2)