anti-Human Phospholipase C gamma 2 antibody for Western Blotting

Recommended Phospholipase C gamma 2 Antibody (supplied by: Log in to see )

Antigen
Phospholipase C gamma 2 (PLCG2) Antibodies
  • PLCgamma2
  • Plcg-2
  • APLAID
  • FCAS3
  • phospholipase C, gamma 2
  • phospholipase C gamma 2
  • phospholipase C, gamma 2 (phosphatidylinositol-specific)
  • Plcg2
  • PLCG2
Reactivity
Mouse (Murine), Rat (Rattus), Human
282
173
162
12
4
4
4
4
3
1
Host
Rabbit
230
52
Clonality
Polyclonal
Conjugate
This Phospholipase C gamma 2 antibody is un-conjugated
6
6
5
5
5
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
203
110
63
60
44
40
36
16
14
10
3
3
2
1
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Catalog No. ABIN3023145
$ 393.25
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
28.55837 ABIN5542312 ELISA FACS ICC IHC WB Mouse IgG1 AA 826-985 Log in to see 2D9E8 0
25.55837 ABIN5611155 ELISA FACS ICC WB Mouse IgG2b pTyr753 Log in to see 3A8B6 0
25.55837 ABIN5542311 ELISA FACS ICC IHC WB Mouse IgG1 AA 826-985 Log in to see 1E10C11 0
16.802607 ABIN4880951 ELISA FACS ICC WB Mouse IgG1 AA 826-985 Log in to see 2D9E8 0
16.802607 ABIN5692854 ELISA IHC WB Rabbit AA 1201-1258 Log in to see Polyclonal 0
16.55837 ABIN3182494 ELISA IHC WB Rabbit IgG pTyr753 Log in to see Polyclonal 0
16.55837 ABIN3186506 ELISA IHC WB Rabbit IgG Thr246 Log in to see Polyclonal 0
13.802607 ABIN4880950 ELISA IHC WB Mouse IgG1 AA 826-985 Log in to see 1E10C11 0
13.802607 ABIN4881227 ELISA FACS ICC WB Mouse IgG2b pTyr753 Log in to see 3A8B6 0
13.802607 ABIN6256017 ELISA ICC IF IHC WB Rabbit IgG pTyr753 Log in to see Polyclonal 0
13.802607 ABIN6264289 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
13.802607 ABIN948268 IP WB Rabbit AA 1-1265, full length Log in to see Polyclonal 0
13.802607 ABIN518950 PLA WB Mouse AA 1-1265, full length Log in to see Polyclonal 0
13.802607 ABIN518951 PLA WB Rabbit AA 1-1265, full length Log in to see Polyclonal 0
12.755764 ABIN3182765 ELISA IF IHC WB Rabbit IgG pTyr1217 Log in to see Polyclonal 0
12.755764 ABIN3186505 ELISA IHC WB Rabbit IgG Thr2446 Log in to see Polyclonal 0
12.755764 ABIN5618571 ELISA IF IHC WB Rabbit IgG pTyr1217 Log in to see Polyclonal 0
12.755764 ABIN5618574 ELISA IHC WB Rabbit IgG Tyr1217 Log in to see Polyclonal 0
12.755764 ABIN1842474 IF WB Rabbit IgG pTyr753 Log in to see Polyclonal 0
12.755764 ABIN5618573 WB Rabbit IgG pTyr753 Log in to see Polyclonal 0

General

Antigen Phospholipase C gamma 2 (PLCG2) Antibodies
Reactivity Mouse (Murine), Rat (Rattus), Human
(282), (173), (162), (12), (4), (4), (4), (4), (3), (1)
Host Rabbit
(230), (52)
Clonality
Polyclonal
Conjugate This Phospholipase C gamma 2 antibody is un-conjugated
(6), (6), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(203), (110), (63), (60), (44), (40), (36), (16), (14), (10), (3), (3), (2), (1)
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Product Details anti-Phospholipase C gamma 2 Antibody

Target Details Phospholipase C gamma 2 Application Details Handling Images
Purification Affinity purification
Immunogen Recombinant protein of human PLCG2
Isotype IgG
Plasmids, Primers & others

Target Details Phospholipase C gamma 2

Product Details anti-Phospholipase C gamma 2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PLCG2 (PLCG2 Antibody Abstract)
Background Phosphoinositide-specific phospholipase C (PLC) plays a significant role in transmembrane signaling. In response to extracellular stimuli such as hormones, growth factors and neurotransmitters, PLC hydrolyzes phosphatidylinositol 4, 5-bisphosphate (PIP2) to generate two secondary messengers: inositol 1, 4, 5-triphosphate (IP3) and diacylglycerol (DAG). At least four families of PLCs have been identified: PLCbeta, PLCgamma, PLCdelta and PLCepsilon. The PLCbeta subfamily includes four members, PLCbeta1-4. All four members of the subfamily are activated by alpha- or beta-gamma-subunits of the heterotrimeric G-proteins.Phosphorylation is one of the key mechanisms that regulates the activity of PLC. Phosphorylation of Ser1105 by PKA or PKC inhibits PLCbeta3 activity. Ser537 of PLCbeta3 is phosphorylated by CaMKII, and this phosphorylation may contribute to the basal activity of PLCbeta3. PLCgamma is activated by both receptor and nonreceptor tyrosine kinases.PLCgamma forms a complex with EGF and PDGF receptors, which leads to the phosphorylation of PLCgamma at Tyr771, 783 and 1245. Phosphorylation by Syk at Tyr783 activates the enzymatic activity of PLCgamma1. PLCgamma2 is engaged in antigen-dependent signaling in B cells and collagen-dependent signaling in platelets. Phosphorylation by Btk or Lck at Tyr753, 759, 1197 and 1217 is correlated with PLCgamma2 activity.
Synonyms: PLCG2, APLAID, FCAS3
Gene ID 5336
UniProt P16885
Pathways RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling

Application Details

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Handling Images back to top
Application Notes Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Restrictions For Research Use only

Handling

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

Images

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Phospholipase C gamma 2 (PLCG2) antibody (ABIN3023145) anti-Phospholipase C gamma 2 (PLCG2) antibody
Immunofluorescence (IF) image for anti-Phospholipase C gamma 2 (PLCG2) antibody (ABIN3023145) Immunofluorescence analysis of HeLa cell using PLCG2 antibody.
Western Blotting (WB) image for anti-Phospholipase C gamma 2 (PLCG2) antibody (ABIN3023145) Western blot analysis of extracts of various cell lines, using PLCG2 antibody.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Phospholipase C gamma 2 (PLCG2) antibody (ABIN3023145) Immunohistochemistry of paraffin-embedded mouse heart using PLCG2 antibody.
Immunofluorescence (IF) image for anti-Phospholipase C gamma 2 (PLCG2) antibody (ABIN3023145) Immunofluorescence analysis of U2OS cells using PLCG2 antibody.