SIGMAR1 Products
(sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
Categories
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor\; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2008].
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Featured SIGMAR1 Categories
SIGMAR1 Antibodies
High quality antibodies with extensive validation data.
SIGMAR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SIGMAR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SIGMAR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (1)
- (3)
Cat. No.
ABIN389221
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7169599
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN709841
Quantity
100 μL
Datasheet
Datasheet
Recommended SIGMAR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow
Analytical Method
Quantitative
Validations
Cat. No.
ABIN1058417
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Quantitative
Validations
Cat. No.
ABIN1058418
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Quantitative
Validations
Cat. No.
ABIN1058419
Quantity
96 tests
Datasheet
Datasheet
Recommended SIGMAR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1790001
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3131913
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3117656
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SIGMAR1 products
: "Sigma-1 Receptor Antagonist (BD1047) Decreases Cathepsin B Secretion in HIV-Infected Macrophages Exposed to Cocaine." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, (2018) (PubMed).: "TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 7, pp. E1657-E1666, (2018) (PubMed).
: "The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis. ..." in: Oncogene, Vol. 36, Issue 25, pp. 3640-3647, (2017) (PubMed).
: "The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands." in: The Biochemical journal, Vol. 466, Issue 2, pp. 263-71, (2015) (PubMed).
: "Modeling tandem AAG8-MEK inhibition in melanoma cells." in: Cancer medicine, Vol. 3, Issue 3, pp. 710-8, (2014) (PubMed).
: "Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances." in: Cell death & disease, Vol. 5, pp. e1290, (2014) (PubMed).
: "Sigma-1 receptor enhances neurite elongation of cerebellar granule neurons via TrkB signaling." in: PLoS ONE, Vol. 8, Issue 10, pp. e75760, (2013) (PubMed).
: "Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis." in: Human molecular genetics, Vol. 22, Issue 8, pp. 1581-600, (2013) (PubMed).
: "The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation." in: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4569-79, (2012) (PubMed).
: "An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for ..." in: European journal of pharmacology, Vol. 578, Issue 2-3, pp. 123-36, (2008) (PubMed).
Synonyms and alternative names related to SIGMAR1
sigma non-opioid intracellular receptor 1 (SIGMAR1), sigma non-opioid intracellular receptor 1 (Sigmar1), sigma non-opioid intracellular receptor 1 L homeolog (sigmar1.L), sigma non-opioid intracellular receptor 1 (sigmar1), AL024364, ALS16, mSigmaR1, OPRS1, Oprs1, oprs1, SIG-1R, sigma1R, Sigma1R, SR-BP, SR-BP1, SRBP, zgc:56378Protein level used designations for SIGMAR1
- SR31747 binding protein 1
- aging-associated gene 8 protein
- hSigmaR1
- sigma 1-type opioid receptor
- opioid receptor, sigma 1
- sigma1-receptor
- sigma1R
- Sigma 1-type opioid receptor
- Sigma1-receptor
- sigma1-receptor (sterol-isomerase like protein)
- sterol isomerase-like protein
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