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Signal Transducing Adaptor Family Member 2 Products

(Signal Transducing Adaptor Family Member 2 (STAP2))
This gene encodes the substrate of breast tumor kinase, an Src-type non-receptor tyrosine kinase. The encoded protein possesses domains and several tyrosine phosphorylation sites characteristic of adaptor proteins that mediate the interactions linking proteins involved in signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

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Featured Signal Transducing Adaptor Family Member 2 Categories

Signal Transducing Adaptor Family Member 2 Antibodies

High quality antibodies with extensive validation data.

Signal Transducing Adaptor Family Member 2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Signal Transducing Adaptor Family Member 2 Antibodies

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Cat. No.
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Reactivity Human
Application WB, ELISA
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Cat. No. ABIN184610
Quantity 100 μg
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Reactivity Human
Application WB, IHC (p), ICC, IF
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Cat. No. ABIN2856300
Quantity 100 μL
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Reactivity Human
Application WB, ELISA
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Cat. No. ABIN1774860
Quantity 100 μg
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Recommended Signal Transducing Adaptor Family Member 2 Proteins

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Quantity 10 μg
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Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3077407
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Reactivity Mouse
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Cat. No. ABIN3126569
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Latest Publications for our Signal Transducing Adaptor Family Member 2 products

Palzur, Sharon, Shehadeh, Soustiel: "Investigation of the mechanisms of neuroprotection mediated by Ro5-4864 in brain injury." in: Neuroscience, Vol. 329, pp. 162-70, (2017) (PubMed).

Jiang, Wang, Wang, Hawke, Zheng, Li, Zhou, Majumder, Bi, Liu, Huang, Lu: "PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells." in: Nature communications, Vol. 5, pp. 5566, (2015) (PubMed).

Chen, Hong, Chen, Fan, Zhang, Zhang, Zhu: "Distinctive expression and cellular distribution of dopamine receptors in the pancreatic islets of rats." in: Cell and tissue research, Vol. 357, Issue 3, pp. 597-606, (2014) (PubMed).

Ikeda, Mizushima, Sekine, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: "Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells." in: Cancer science, Vol. 102, Issue 4, pp. 756-61, (2011) (PubMed).

Ikeda, Sekine, Mizushima, Nakasuji, Miyasaka, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: "Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells." in: The Journal of biological chemistry, Vol. 285, Issue 49, pp. 38093-103, (2010) (PubMed).

Ikeda, Miyasaka, Sekine, Mizushima, Muromoto, Nanbo, Yoshimura, Matsuda: "STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation." in: Biochemical and biophysical research communications, Vol. 384, Issue 1, pp. 71-5, (2009) (PubMed).

Sekine, Ikeda, Tsuji, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: "Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 12, pp. 7966-74, (2009) (PubMed).

Minoguchi, Minoguchi, Aki, Joo, Yamamoto, Yumioka, Matsuda, Yoshimura: "STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif." in: The Journal of biological chemistry, Vol. 278, Issue 13, pp. 11182-9, (2003) (PubMed).

Mitchell, Sara, Crompton: "A novel adaptor-like protein which is a substrate for the non-receptor tyrosine kinase, BRK." in: Oncogene, Vol. 19, Issue 37, pp. 4273-82, (2000) (PubMed).

Synonyms and alternative names related to Signal Transducing Adaptor Family Member 2

signal transducing adaptor family member 2 (STAP2), signal transducing adaptor family member 2 (Stap2), signal transducing adaptor family member 2b (stap2b), signal transducing adaptor family member 2a (stap2a), AW049765, BKS, cb901, STAP-2, stap2, wu:fa55b07, wu:fd15d07, zgc:63913, zgc:77021

Protein level used designations for Signal Transducing Adaptor Family Member 2

  • BRK substrate
  • breast tumor kinase substrate
  • brk kinase substrate
  • signal-transducing adaptor protein 2
  • signal-transducing adaptor protein-2
  • signal transducing adaptor family member 2
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