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SIX3 Products

(Sine Oculis-Related Homeobox 3 (SIX3))

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This gene encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in this gene have been associated with holoprosencephaly type 2. [provided by RefSeq, Oct 2009].

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Featured SIX3 Categories

SIX3 Antibodies

High quality antibodies with extensive validation data.

SIX3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SIX3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application ELISA, FM, IHC, WB
Validations
  • (2)
  • (4)
Cat. No. ABIN6657910
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (5)
Cat. No. ABIN520208
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (4)
Cat. No. ABIN520204
Quantity 100 μg
Datasheet Datasheet

Recommended SIX3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095435
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135533
Quantity 1 mg
Datasheet Datasheet
Reactivity Killifish (Oryzias latipes)
Source Yeast
Validations
Cat. No. ABIN1656075
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SIX3 products

Lipiec, Bem, Koziński, Chakraborty, Urban-Ciećko, Zajkowski, Dąbrowski, Szewczyk, Toval, Ferran, Nagalski, Wiśniewska: "TCF7L2 regulates postmitotic differentiation programmes and excitability patterns in the thalamus." in: Development (Cambridge, England), Vol. 147, Issue 16, (2021) (PubMed).

Li, Xie, He, Zhou, Gao, Liu, Pan, Ge, Peng, Zhong: "Generation of Retinal Organoids with Mature Rods and Cones from Urine-Derived Human Induced Pluripotent Stem Cells." in: Stem cells international, Vol. 2018, pp. 4968658, (2018) (PubMed).

Diacou, Zhao, Zheng, Cvekl, Liu: "Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation." in: Cell reports, Vol. 25, Issue 9, pp. 2510-2523.e4, (2018) (PubMed).

Xu, Liang, Song, Zhang, Lindtner, Li, Wen, Liu, Guo, Qi, Wang, Wang, Li, You, Wang, Chen, Feng, Rubenstein, Yang: "SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression." in: Development (Cambridge, England), Vol. 145, Issue 14, (2018) (PubMed).

OBrien, Guo, Bahrami-Samani, Park, Hasso, Lee, Fang, Kim, Guo, Hong, Peterson, Lozanoff, Raviram, Ren, Fogelgren, Smith, Valouev, McMahon: "Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies." in: PLoS genetics, Vol. 14, Issue 1, pp. e1007181, (2018) (PubMed).

Madrigal, Moreno-Bravo, Martínez-López, Martínez, Puelles: "Mesencephalic origin of the rostral Substantia nigra pars reticulata." in: Brain structure & function, Vol. 221, Issue 3, pp. 1403-12, (2016) (PubMed).

Moldrich, Gobius, Pollak, Zhang, Ren, Brown, Mori, De Juan Romero, Britanova, Tarabykin, Richards: "Molecular regulation of the developing commissural plate." in: The Journal of comparative neurology, Vol. 518, Issue 18, pp. 3645-61, (2010) (PubMed).

Liu, Lagutin, Mende, Streit, Oliver: "Six3 activation of Pax6 expression is essential for mammalian lens induction and specification." in: The EMBO journal, Vol. 25, Issue 22, pp. 5383-95, (2006) (PubMed).

Ando, Kobayashi, Tsubokawa, Uyemura, Furuta, Okamoto: "Lhx2 mediates the activity of Six3 in zebrafish forebrain growth." in: Developmental biology, Vol. 287, Issue 2, pp. 456-68, (2005) (PubMed).

Lagutin, Zhu, Furuta, Rowitch, McMahon, Oliver: "Six3 promotes the formation of ectopic optic vesicle-like structures in mouse embryos." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 221, Issue 3, pp. 342-9, (2001) (PubMed).

Synonyms and alternative names related to SIX3

SIX homeobox 3 (SIX3), SIX homeobox 3b (six3b), sine oculis-related homeobox 3 (Six3), SIX homeobox 3 (Six3), sine oculis homeobox homolog 3 (six3), cb347, E130112M24Rik, HPE2, SIX3, six3.2, Six3a, Six3alpha, Six3b, Six3beta, six6

Protein level used designations for SIX3

  • homeobox protein SIX3
  • sine oculis homeobox homolog 3
  • sine oculis homeobox homolog 6
  • sine oculis-related homeobox 3 homolog
  • CSIX3
  • sine oculis homeobox 3-like protein
  • Sine oculis homeobox homolog 3
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