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Sorting Nexin 1 Products

(Sorting Nexin 1 (SNX1))

Categories

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

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Featured Sorting Nexin 1 Categories

Sorting Nexin 1 Antibodies

High quality antibodies with extensive validation data.

Sorting Nexin 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Sorting Nexin 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Sorting Nexin 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC (p), RNAi, ELISA, WB
Validations
  • (6)
Cat. No. ABIN562947
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, ICC, IHC, WB
Validations
  • (4)
Cat. No. ABIN571095
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7171199
Quantity 100 μg
Datasheet Datasheet

Recommended Sorting Nexin 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970376
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1159149
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1159150
Quantity 96 tests
Datasheet Datasheet

Recommended Sorting Nexin 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3137529
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5711327
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320852
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Sorting Nexin 1 products

Mari, Bujny, Zeuschner, Geerts, Griffith, Petersen, Cullen, Klumperman, Geuze: "SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors." in: Traffic (Copenhagen, Denmark), Vol. 9, Issue 3, pp. 380-93, (2008) (PubMed).

Nielsen, Gustafsen, Madsen, Nyengaard, Hermey, Bakke, Mari, Schu, Pohlmann, Dennes, Petersen: "Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA." in: Molecular and cellular biology, Vol. 27, Issue 19, pp. 6842-51, (2007) (PubMed).

Cozier, Carlton, McGregor, Gleeson, Teasdale, Mellor, Cullen: "The phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradation." in: The Journal of biological chemistry, Vol. 277, Issue 50, pp. 48730-6, (2002) (PubMed).

Kurten, Eddington, Chowdhury, Smith, Davidson, Shank: "Self-assembly and binding of a sorting nexin to sorting endosomes." in: Journal of cell science, Vol. 114, Issue Pt 9, pp. 1743-56, (2001) (PubMed).

Strehlow, Jelaska, Strehlow, Korn: "A potential role for protease nexin 1 overexpression in the pathogenesis of scleroderma." in: The Journal of clinical investigation, Vol. 103, Issue 8, pp. 1179-90, (1999) (PubMed).

Haft, de la Luz Sierra, Barr, Haft, Taylor: "Identification of a family of sorting nexin molecules and characterization of their association with receptors." in: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7278-87, (1998) (PubMed).

Kurten, Cadena, Gill: "Enhanced degradation of EGF receptors by a sorting nexin, SNX1." in: Science (New York, N.Y.), Vol. 272, Issue 5264, pp. 1008-10, (1996) (PubMed).

Synonyms and alternative names related to Sorting Nexin 1

sorting nexin 1a (snx1a), sorting nexin 1 L homeolog (snx1.L), sorting nexin 1 (SNX1), sorting nexin 1 (snx1), sorting nexin-1 (LOC100380673), sorting nexin 1 (Snx1), ARABIDOPSIS THALIANA SORTING NEXIN 1, ATSNX1, d254, HsT17379, K16F4.11, K16F4_11, MGC82200, sb:cb923, snx1, SNX1, sorting nexin 1, VPS5, wu:fb40c08, wu:fj65g09

Protein level used designations for Sorting Nexin 1

  • sorting nexin 1
  • nexin 1
  • sorting nexin-1
  • Sorting nexin-1
  • sorting nexin 1A
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