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|Antigen||CD4 Molecule (CD4) Antibodies|
|Conjugate||This CD4 antibody is un-conjugated Alternatives|
Immunohistochemistry (Frozen Sections) (IHC (fro))
|5 references available|
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Product Details anti-CD4 AntibodyTarget Details CD4 Application Details Handling References for anti-CD4 antibody (ABIN3043630) Images
|Purpose||Mouse IgG monoclonal antibody for CD4, CD4 molecule (CD4) detection. Tested with IHC-F in Human. No cross reactivity with other proteins.|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Mouse IgG monoclonal antibody for CD4, CD4 Molecule (CD4) detection. Tested with IHC-F in Human.
Gene Name: CD4 Molecule
Protein Name: T-cell surface glycoprotein CD4
|Immunogen||CD4-transfected mouse T-cell hybridoma, 3DT, followed by CD4+ human T-cell CEM cells.|
|Plasmids, Primers & others|
Target Details CD4Product Details anti-CD4 Antibody Application Details Handling References for anti-CD4 antibody (ABIN3043630) Images back to top
|Alternative Name||CD4 (CD4 Antibody Abstract)|
CD stands for "cluster of differentiation", the number that follows is arbitrarily assigned. In the full designation the cell type and nature and molecular weight of the antigen are given in brackets, for CD4, this is as follows: [T,gp55]. CD4 is present on a subset of T lymphocytes("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Synonyms: CD4 antigen|T-cell surface antigen T4/Leu-3|T-cell surface glycoprotein CD4
|Gene ID||920, 12504, 24932|
|Pathways||TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events|
Application DetailsProduct Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 antibody (ABIN3043630) Images back to top
IHC-F: Concentration: 1 μg/mL, Species: Human
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by ABIN921230 in IHC(F).
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 antibody (ABIN3043630) Images back to top
|Reconstitution||Add 1 mL of PBS buffer will yield a concentration of 100 μg/mL.|
|Buffer||Mouse ascites fluid, 1.2 % sodium acetate, 2 mg BSA, with 0.01 mg Sodium azide as preservative.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
References for anti-CD4 antibody (ABIN3043630)Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
|Product cited in:||
Wang, Shi, Tu, Wang, Zhang, Wang, Zhang, Huang, Zhao, Luan, Wang: "Treating cutaneous squamous cell carcinoma using 5-aminolevulinic acid polylactic-co-glycolic acid nanoparticle-mediated photodynamic therapy in a mouse model." in: International journal of nanomedicine, Vol. 10, pp. 347-55, 2015
Xu, Tan, Wang, Wang, Li, Wu, Chen, Wu, Tan: "Elevated survivin expression in peripheral blood mononuclear cells is central to collateral formation in coronary chronic total occlusion." in: International journal of molecular medicine, Vol. 35, Issue 6, pp. 1501-10, 2015
Wu, Wang, Qi, Zhang, Zhang, Zhang: "Increased macrophage activation inhibited by tacrolimus in the kidney of diabetic rats." in: Nephron. Experimental nephrology, Vol. 128, Issue 1-2, pp. 46-56, 2014
Zhao, Li, He, Qiu, Zhu, Qi: "Interleukin-15 gene therapy and the mammalian target of rapamycin inhibitor everolimus inhibit the growth of metastatic breast cancer." in: The journal of gene medicine, Vol. 15, Issue 10, pp. 366-74, 2013
Chen, Wan, Liu, Xie, Diao, Xu, Zhu, Chen: "Increased IL-17-producing cells correlate with poor survival and lymphangiogenesis in NSCLC patients." in: Lung cancer (Amsterdam, Netherlands), Vol. 69, Issue 3, pp. 348-54, 2010
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