anti-Human CD4 antibody for Immunohistochemistry (Zinc-fixed Sections)

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • L3T4
  • Ly-4
  • CD4mut
  • W3/25
  • p55
  • CD4 molecule
  • carcinoembryonic antigen-related cell adhesion molecule 5
  • T-cell surface glycoprotein CD4
  • CD4 antigen
  • Cd4 molecule
  • CD4
  • LOC100125525
  • cd4
  • Cd4
Reactivity
Human
1271
584
237
71
61
41
36
30
28
26
25
25
22
21
18
18
15
15
13
12
10
9
9
7
5
5
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Host
Mouse
1347
525
303
13
4
2
1
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is un-conjugated
253
223
158
133
44
41
39
32
32
32
29
25
24
21
16
16
16
15
15
15
15
15
15
13
10
10
9
8
8
8
8
7
7
6
5
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
1658
545
462
298
287
275
217
164
94
73
54
39
31
26
21
19
18
14
14
11
11
9
6
5
5
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Options
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Catalog No. ABIN2689229
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General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Human
(1271), (584), (237), (71), (61), (41), (36), (30), (28), (26), (25), (25), (22), (21), (18), (18), (15), (15), (13), (12), (10), (9), (9), (7), (5), (5), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(1347), (525), (303), (13), (4), (2), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is un-conjugated
(253), (223), (158), (133), (44), (41), (39), (32), (32), (32), (29), (25), (24), (21), (16), (16), (16), (15), (15), (15), (15), (15), (15), (13), (10), (10), (9), (8), (8), (8), (8), (7), (7), (6), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(1658), (545), (462), (298), (287), (275), (217), (164), (94), (73), (54), (39), (31), (26), (21), (19), (18), (14), (14), (11), (11), (9), (6), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling Images
Brand BD Pharmingen™
Characteristics The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations. CD4 is also expressed on thymocytes subsets and at lower levels on monocytes and macrophages. CD4 functions as a co-receptor in MHC class II-restricted antigen-induced T cell activation and as a receptor for human immunodeficiency viruses (HIV). This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80 % of thymocytes and 45 % of peripheral blood lymphocytes. CD4 is also present in low density on peripheral blood monocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation. Immunohistochemical staining of CD4+ T lymphocytes: Frozen sections of normal human tonsil was reacted with the RPA-T4 antibody. CD4+ T lymphocytes can be identified by the intense brown labeling of their cell membranes.

BD Pharmingen™ Purified Mouse Anti-Human CD4 - Purified - Clone RPA-T4 - Isotype Mouse IgG1, κ - Reactivity Hu - 1 mL
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Clone RPA
Isotype IgG1, kappa
Plasmids, Primers & others

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Pathways TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details Images back to top
Format Liquid
Concentration 31.25 μg/mL
Buffer Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.