anti-Human LAT antibody for Immunohistochemistry

Recommended LAT Antibody (supplied by: Log in to see )

Antigen
Linker For Activation of T Cells (LAT) Antibodies
  • LAT
  • lat
  • LAT1
  • pp36
  • linker for activation of T-cells
  • linker for activation of T cells
  • LAT
  • lat
  • Lat
Epitope
pTyr161
30
25
22
22
14
7
5
5
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
277
121
103
3
2
1
Host
Rabbit
167
103
13
2
Clonality
Polyclonal
Conjugate
This LAT antibody is un-conjugated
9
9
8
7
7
6
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
213
80
51
50
39
32
32
9
6
2
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN6271566
$ 450.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
18.992594 ABIN393665 ELISA IHC WB Mouse IgG1 kappa AA 1-234 Log in to see 3B11-1D5 5
15.992594 ABIN6269667 ELISA IHC WB Rabbit IgG pTyr45 Log in to see Polyclonal 0
12.992594 ABIN573989 IHC IHC (p) IP WB Mouse IgG1, kappa Log in to see LAT-10-17 (10-17) 0
12.760654 ABIN3182545 ELISA IHC WB Rabbit IgG pTyr191 Log in to see Polyclonal 0
12.760654 ABIN5618163 ELISA IHC WB Rabbit IgG pTyr191 Log in to see Polyclonal 0
10 ABIN1868912 ICC IHC WB Rabbit IgG AA 25-221 Log in to see Polyclonal 0
9.992594 ABIN1531336 IHC ELISA WB Rabbit IgG AA 191-240, pTyr191 Log in to see Polyclonal 0
9.992594 ABIN6269669 ELISA IHC WB Rabbit IgG pSer84 Log in to see Polyclonal 0
9.992594 ABIN6256669 IHC WB Rabbit IgG pTyr200 Log in to see Polyclonal 0
9.992594 ABIN293627 IHC IHC (p) IP WB Mouse IgG1 Cytoplasmic Domain Log in to see LAT1111 0
9.992594 ABIN1102812 IHC IHC (p) WB Rabbit AA 70-120 Log in to see Polyclonal 0
7 ABIN599213 ELISA IHC IHC (p) WB Mouse IgG1, kappa AA 1-234 Log in to see 3B11-1D5 0
6.992594 ABIN2470864 IP IHC WB Mouse IgG1 kappa Log in to see LAT-10-17 (10-17) 0
6.992594 ABIN2470080 IP IHC WB Mouse IgG1 Cytoplasmic Domain Log in to see LAT1111 0
4 ABIN1876851 IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2624774 ICC IHC IHC (p) WB Rabbit IgG AA 242-262 Log in to see Polyclonal 0
1 ABIN342762 IHC ELISA WB Rabbit AA 29-49, N-Term Log in to see Polyclonal 0
1 ABIN2883990 ELISA IHC IHC (p) WB Rabbit IgG pTyr191 Log in to see Polyclonal 0
1 ABIN1819430 IHC IHC (p) Rabbit IgG Log in to see Polyclonal 0
1 ABIN2881203 IHC WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Linker For Activation of T Cells (LAT) Antibodies
Epitope pTyr161
(30), (25), (22), (22), (14), (7), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(277), (121), (103), (3), (2), (1)
Host Rabbit
(167), (103), (13), (2)
Clonality
Polyclonal
Conjugate This LAT antibody is un-conjugated
(9), (9), (8), (7), (7), (6), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(213), (80), (51), (50), (39), (32), (32), (9), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-LAT Antibody

Target Details LAT Application Details Handling Images
Specificity LAT (Phospho-Tyr161) Antibody detects endogenous levels of LAT only when phosphorylated at Tyr161
Cross-Reactivity Human, Mouse (Murine)
Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogen A synthesized peptide derived from human LAT (Phospho-Tyr161)
Isotype IgG
Plasmids, Primers & others

Target Details LAT

Product Details anti-LAT Antibody Application Details Handling Images back to top
Antigen
Alternative Name LAT (LAT Antibody Abstract)
Background

Description: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Gene: LAT

Molecular Weight 28kDa
Gene ID 27040
UniProt O43561
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-LAT Antibody Target Details LAT Handling Images back to top
Application Notes WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-LAT Antibody Target Details LAT Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-LAT Antibody Target Details LAT Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN6271566) ABIN6271567 at 1/200 staining Human kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN6271566) ABIN6271567 at 1/200 staining Mouse kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN6271566) ABIN6271567 at 1/200 staining Rat spleen tissue sections by IHC-P. The tissue was for...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN6271566) ABIN6271567 staining NIH-3T3 by IF/ICC. The sample were fixed with PFA and permeabili...
Western Blotting (WB) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN6271566) Western blot analysis of extracts from 293, using LAT (Phospho-Tyr161) Antibody.
Western Blotting (WB) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN6271566) Western blot analysis of LAT (Phospho-Tyr161) using EGF treated 293 whole cell lysates
Immunohistochemistry (IHC) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN6271566) ABIN6271567 at 1/200 staining Human kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN6271566) ABIN6271567 at 1/200 staining Mouse kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Linker For Activation of T Cells (LAT) (pTyr161) antibody (ABIN6271566) ABIN6271567 at 1/200 staining Rat spleen tissue sections by IHC-P. The tissue was for...